Evidence map›Paper›PMID 38745084›Full record

ArticleEye (London, England)2024

The Wisconsin silicone oil study (report #1): anatomical and functional outcomes of repair of retinal detachment with proliferative vitreoretinopathy.

Kathleen R Schildroth, Maxwell J Wingelaar, Paul S Boeke, Michael S Ip, Jonathan S Chang, Justin L Gottlieb, T Michael Nork, Kyle Peterson, Michael M Altaweel

Abstract read
In one paragraph

Article in Eye (London, England), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Kathleen R SchildrothUniversity of Wisconsin, Department of Ophthalmology and Visual Sciences, Madison, WI, USA.ORCID http://orcid.org/0000-0003-0504-3053
Maxwell J WingelaarUniversity of Wisconsin, Department of Ophthalmology and Visual Sciences, Madison, WI, USA.
Paul S BoekeUniversity of Wisconsin, Department of Ophthalmology and Visual Sciences, Madison, WI, USA.
Michael S IpDoheny Eye Institute, University of California - Los Angeles, Los Angeles, CA, USA.
Jonathan S ChangUniversity of Wisconsin, Department of Ophthalmology and Visual Sciences, Madison, WI, USA.ORCID http://orcid.org/0000-0001-5693-5065
Justin L GottliebUniversity of Wisconsin, Department of Ophthalmology and Visual Sciences, Madison, WI, USA.
T Michael NorkUniversity of Wisconsin, Department of Ophthalmology and Visual Sciences, Madison, WI, USA.ORCID http://orcid.org/0000-0002-0687-373X
Kyle PetersonUniversity of Wisconsin, Department of Ophthalmology and Visual Sciences, Madison, WI, USA.
Michael M AltaweelUniversity of Wisconsin, Department of Ophthalmology and Visual Sciences, Madison, WI, USA. mmaltaweel@wisc.edu.ORCID http://orcid.org/0000-0003-1554-3211

Funding

UW Vision Research Core - Administrative CoreP30EY016665 · NEI · UNIVERSITY OF WISCONSIN-MADISON · PI ROBERT W NICKELLS · 2005 to 2026
$12.6M
NEI NIH HHS P30 EY016665
6 · The paper itself

Abstract

backgroundSilicone oil (SO) is a long-term tamponade for repair of complex retinal pathology but has limitations including late redetachment. This study describes our experience with SO tamponade for repair of retinal detachment with proliferative vitreoretinopathy (PVR), with attention to anatomic and functional outcomes.

methodsRetrospective consecutive case series of eyes with retinal detachment (RD) complicated by proliferative vitreoretinopathy (PVR) receiving SO tamponade at the University of Wisconsin between 2013 and 2019. Group 1 defined as primary SO placement; Group 2 had SO placed after failing prior retinal detachment repair.

resultsInclusion criteria of SO placement for repair of RD with PVR was met for 117 eyes. The final reattachment rate was 84% for all eyes, with no difference between Groups 1 and 2. Vision improvement was 2.1 lines for Group 1 (p = 0.06 from baseline) and 4.6 lines for Group 2 (p < 0.0001). The mean number of silicone oil placements was 1.4. Less improvement in vision was noted with repeat SO placement, though overall functional vision of 5/200 or better was achieved in 63.2% of patients.

conclusionsSO tamponade allows long-term anatomical stabilisation and substantial vision recovery in eyes with retinal detachment complicated by PVR. Rates of anatomic and functional success have improved significantly when compared to prior studies using oil tamponade for repair of PVR.

Indexed as

EndotamponadeRetinal DetachmentSilicone OilsVisual AcuityVitrectomyVitreoretinopathy, ProliferativeAdultAgedFemaleFollow-Up StudiesHumansMaleMiddle AgedRetrospective StudiesTreatment OutcomeWisconsinSilicone Oils

Identifiers

PMID38745084
PMCPMC11427578

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.