Evidence map›Paper›PMID 38745029›Full record

ArticlePediatric research2024

Evaluating eight indicators for identifying metabolic syndrome in Chinese and American adolescents.

Xuan Hu, Zhuoqiao Yang, Wenxin Ge, Yaling Ding, Yi Zhong, Jianing Long, Xiaoyan Zhu, Jia Hu, Jieyun Yin

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Article in Pediatric research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

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3citing papers in PubMed
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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

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3 · Its place in the literature

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3 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Xuan Hu *Department of Epidemiology and Health Statistics, Medical College of Soochow University, Suzhou, Jiangsu, China.
Zhuoqiao Yang *Department of Epidemiology and Health Statistics, Medical College of Soochow University, Suzhou, Jiangsu, China.
Wenxin GeDepartment of Maternal and Child Health, School of Public Health, Sun Yat-sen University, Guangzhou, China.
Yaling DingDepartment of Epidemiology and Health Statistics, Medical College of Soochow University, Suzhou, Jiangsu, China.
Yi ZhongDepartment of Epidemiology and Health Statistics, Medical College of Soochow University, Suzhou, Jiangsu, China.
Jianing LongDepartment of Epidemiology and Health Statistics, Medical College of Soochow University, Suzhou, Jiangsu, China.
Xiaoyan ZhuSuzhou Center for Disease Prevention and Control, Suzhou, Jiangsu, China.
Jia HuSuzhou Center for Disease Prevention and Control, Suzhou, Jiangsu, China. hujia200606@163.com.
Jieyun YinDepartment of Epidemiology and Health Statistics, Medical College of Soochow University, Suzhou, Jiangsu, China. jyyin@suda.edu.cn.ORCID 0000-0002-5265-3930

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEarly intervention and diagnosis of Metabolic Syndrome (MetS) are crucial for preventing adult cardiovascular disease. However, the optimal indicator for identifying MetS in adolescent remains controversial.

methodsIn total,1408 Chinese adolescents and 3550 American adolescents aged 12-17 years were included. MetS was defined according to the modified version for adolescents based on Adult Treatment Panel III (NCEP-ATP III) criteria. Areas under the curve (AUC) and corresponding 95% confidence interval (95% CI) of 8 anthropometric/metabolic indexes, such as waist circumference (WC), body mass index (BMI), a body shape index (ABSI), waist triglyceride index (WTI), were calculated to illustrate their ability to differentiate MetS. Sensitivity analysis using the other MetS criteria was performed.

resultsUnder the modified NCEP-ATP III criteria, WTI had the best discriminating ability in overall adolescents, with AUC of 0.922 (95% CI: 0.900-0.945) in Chinese and 0.959 (95% CI: 0.949-0.969) in American. In contrast, ABSI had the lowest AUCs. Results of sensitivity analysis were generally consistent for the whole Chinese and American population, with the AUC for WC being the highest under some criteria, but it was not statistically different from that of WTI.

conclusionsWTI had relatively high discriminatory power for MetS detection in Chinese and American adolescents, but the performance of ABSI was poor. IMPACT: While many studies have compared the discriminatory power of some anthropometric indicators for MetS, there are few focused on pediatrics. The current study is the first to compare the discriminating ability of anthropometric/metabolic indicators (WC, BMI, TMI, ABSI, WHtR, VAI, WTI, and TyG) for MetS in adolescents. WTI remains the optimal indicator in screening for MetS in adolescents. WC was also a simple and reliable indicator when screening for MetS in adolescents, but the performance of ABSI was poor. This study provides a theoretical basis for the early identification of MetS in adolescents by adopting effective indicators.

Indexed as

Body Mass IndexMetabolic SyndromeWaist CircumferenceAdolescentAnthropometryArea Under CurveChildChinaEast Asian PeopleFemaleHumansMaleTriglyceridesUnited StatesTriglycerides

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.