Evidence map›Paper›PMID 38744809›Full record

ArticleCell death & disease2024

METTL8 links mt-tRNA m

Bernice Woon Li Lee, You Heng Chuah, Jeehyun Yoon, Oleg V Grinchuk, Yajing Liang, Jayshree L Hirpara, Yating Shen, Loo Chien Wang, Yan Ting Lim, Tianyun Zhao and 11 more

Erratum issuedAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cell death & disease, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
  4. Review
  5. Article
  6. Review
  7. Review
  8. Review
  9. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

21 authors.

Bernice Woon Li Lee *Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, 117593, Singapore.
You Heng Chuah *Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, 117593, Singapore.
Jeehyun Yoon *Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, 117593, Singapore.
Oleg V Grinchuk *Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, 117593, Singapore.
Yajing LiangDepartment of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, 117593, Singapore.
Jayshree L HirparaCancer Science Institute of Singapore, National University of Singapore, Singapore, 117599, Singapore.ORCID 0000-0002-1454-9163
Yating ShenThe N.1 Institute for Health, National University of Singapore, Singapore, Singapore.
Loo Chien WangFunctional Proteomics Laboratory, SingMass National Laboratory, Institute of Molecular and Cell Biology, Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.
Yan Ting LimFunctional Proteomics Laboratory, SingMass National Laboratory, Institute of Molecular and Cell Biology, Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.
Tianyun ZhaoFunctional Proteomics Laboratory, SingMass National Laboratory, Institute of Molecular and Cell Biology, Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.
Radoslaw M SobotaFunctional Proteomics Laboratory, SingMass National Laboratory, Institute of Molecular and Cell Biology, Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.ORCID 0000-0002-2455-2526
Tseng Tsai YeoDepartment of Surgery, Division of Neurosurgery, National University Hospital, Singapore, Singapore.
Andrea Li Ann WongCancer Science Institute of Singapore, National University of Singapore, Singapore, 117599, Singapore.
Kejia TeoDepartment of Surgery, Division of Neurosurgery, National University Hospital, Singapore, Singapore.
Vincent Diong Weng NgaDepartment of Surgery, Division of Neurosurgery, National University Hospital, Singapore, Singapore.
Bryce Wei Quan TanDepartment of Medicine, National University Hospital, Singapore, Singapore.
Toshio SudaCancer Science Institute of Singapore, National University of Singapore, Singapore, 117599, Singapore.
Tan Boon TohThe N.1 Institute for Health, National University of Singapore, Singapore, Singapore.ORCID 0000-0003-0292-6985
Shazib PervaizDepartment of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, 117593, Singapore.ORCID 0000-0002-4738-019X
Zhewang LinDepartment of Biological Sciences, 14 Science Drive 4, National University of Singapore, 117543, Singapore, Singapore.
Derrick Sek Tong OngDepartment of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, 117593, Singapore. phsostd@nus.edu.sg.ORCID 0000-0001-7529-3790

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Epitranscriptomic RNA modifications are crucial for the maintenance of glioma stem cells (GSCs), the most malignant cells in glioblastoma (GBM). 3-methylcytosine (m

Indexed as

GlioblastomaHypoxia-Inducible Factor 1, alpha SubunitMethyltransferasesNeoplastic Stem CellsProto-Oncogene Proteins c-aktRNA MethylationAnimalsBrain NeoplasmsCarcinogenesisCell Line, TumorCell ProliferationGene Expression Regulation, NeoplasticHumansMiceMice, NudeMitochondriaHypoxia-Inducible Factor 1, alpha SubunitMethyltransferasesMETTL8 protein, humanProto-Oncogene Proteins c-aktReceptor Protein-Tyrosine KinasesRNA, Transfer

Identifiers

PMID38744809
PMCPMC11093979

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.