Evidence map›Paper›PMID 38744770›Full record

ArticleBrazilian journal of microbiology : [publication of the Brazilian Society for Microbiology]2024

Antimicrobial and antibiofilm activities of Brazilian organic honey against oral microorganisms.

Diego Romário-Silva, Marcelo Franchin, Severino Matias Alencar, Bruno Bueno-Silva, Janaína de Cássia Orlandi Sardi, Andréa Cristina Barbosa da Silva, Fabiane Cruz-Vieira, Priscila Vieira da Silva, Pedro Luiz Rosalen

Abstract read
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In one paragraph

Article in Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology], 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Diego Romário-SilvaDepartment of Biosciences, Piracicaba Dental School, University of Campinas (UNICAMP), Av. Limeira, 901 - Areião, Piracicaba, SP, 13414-903, Brazil.ORCID http://orcid.org/0000-0001-9724-0147
Marcelo FranchinSchool of Dentistry, Federal University of Alfenas (Unifal-MG), Alfenas, MG, Brazil.ORCID http://orcid.org/0000-0001-5613-2756
Severino Matias AlencarDepartment of Agri-Food Industry, Food and Nutrition, "Luiz de Queiroz" College of Agriculture, University of São Paulo (USP), Piracicaba, SP, 13418-900, Brazil.ORCID http://orcid.org/0000-0002-6637-7973
Bruno Bueno-SilvaDepartment of Biosciences, Piracicaba Dental School, University of Campinas (UNICAMP), Av. Limeira, 901 - Areião, Piracicaba, SP, 13414-903, Brazil.ORCID http://orcid.org/0000-0003-3275-5910
Janaína de Cássia Orlandi SardiDental Research Division, Guarulhos University, Guarulhos, SP, 07023-070, Brazil.ORCID http://orcid.org/0000-0002-8500-2691
Andréa Cristina Barbosa da SilvaDepartment of Pharmacy, Center of Biological and Health Sciences, State University of Paraíba, Campina Grande, Piracicaba, PB, 58429-500, Brazil.ORCID http://orcid.org/0000-0001-8964-8919
Fabiane Cruz-VieiraGraduate Program in Integrated Dental Sciences, School of Dentistry, University of Cuiabá, Cuiabá, MT, 78065-900, Brazil.ORCID http://orcid.org/0009-0006-2956-7627
Priscila Vieira da SilvaGraduate Program in Integrated Dental Sciences, School of Dentistry, University of Cuiabá, Cuiabá, MT, 78065-900, Brazil.ORCID http://orcid.org/0000-0002-6295-2344
Pedro Luiz RosalenDepartment of Biosciences, Piracicaba Dental School, University of Campinas (UNICAMP), Av. Limeira, 901 - Areião, Piracicaba, SP, 13414-903, Brazil. rosalen@fop.unicamp.br.ORCID http://orcid.org/0000-0003-0812-4027

Funding

Conselho Nacional de Desenvolvimento Científico e Tecnológico 141129/2017-4
6 · The paper itself

Abstract

objectiveTo evaluate the antimicrobial activity of Brazilian honeys against oral microorganisms.

designOrganic honeys (OH-1 to OH-8) were diluted (%-w/v) and sterilized by filtration. Antimicrobial activity was defined by determining MIC and CBM against oral Streptococcus. The component responsible for the antimicrobial action was defined by a catalase assay. Antibiofilm activity was evaluated against the monospecies biofilm of Streptococcus mutans  (ATCC 700610).

resultsOHs showed antimicrobial activity principally OH-1, OH-2, OH-3, and OH-7 with MIC values ​​ranging between 10 and 25%. The mechanism of action occurs mainly by hydrogen peroxide produced by honey enzymes. OH-1, OH-2, and OH-7 showed total biofilm destruction at low concentrations.

conclusionBrazilian honeys have promising antimicrobial and antibiofilm activity with the potential to control oral microbiota.

Indexed as

Anti-Bacterial AgentsBiofilmsHoneyMicrobial Sensitivity TestsMouthBrazilHumansStreptococcusStreptococcus mutansAnti-Bacterial AgentsAntibiofilm activityAntimicrobial activityHoneyOral microorganism

Identifiers

PMID38744770
PMCPMC11405583

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.