Evidence map›Paper›PMID 38744729›Full record

Observational studyActa neurochirurgica2024

Clinical outcomes of posterior fossa arteriovenous malformations: a single center experience.

Ioana Miron, Viorel M Prună, Dan Visarion, Andrei Giovani, Aurelia M Sandu, Felix M Brehar, George E D Petrescu, Radu M Gorgan

Abstract readObservational Study
In one paragraph

Observational study in Acta neurochirurgica, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ioana MironDepartment of Neurosurgery, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania.ORCID 0009-0000-6016-0186
Viorel M PrunăDepartment of Neurosurgery, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania.ORCID 0000-0001-8488-4250
Dan VisarionDepartment of Neurosurgery, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania.
Andrei GiovaniDepartment of Neurosurgery, Bagdasar-Arseni Clinical Emergency Hospital, Bucharest, Romania.
Aurelia M SanduDepartment of Neurosurgery, Bagdasar-Arseni Clinical Emergency Hospital, Bucharest, Romania.
Felix M BreharDepartment of Neurosurgery, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania.
George E D PetrescuDepartment of Neurosurgery, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania. george.petrescu@umfcd.ro.ORCID 0000-0003-2651-3608
Radu M GorganDepartment of Neurosurgery, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPosterior fossa arterio-venous malformations (pfAVMs) are challenging lesions due to the anatomical particularities of the posterior fossa, and the high incidence of hemorrhagic presentation. The two most important goals when treating AVMs are preserving neurological function and preventing rupture, or a second hemorrhage. The aim of this study was to analyze the clinical and imaging features of pfAVMs to identify the factors that influence the prognosis of these patients.

methodsWe conducted a single-center retrospective observational study that included patients treated at our institution with pfAVMs between January 1997 and December 2021.

resultsA total of 48 patients were included. A good modified Rankin score (mRS) was observed in 33 cases (69%) at presentation. Thirty-four patients (71%) presented with a ruptured AVM. Out of these, 19 patients (40%) had intraventricular hemorrhage. Microsurgical resection was performed in 33 cases (69%), while in the other cases, the patients opted for conservative management (7 cases, 15%), stereotactic radiosurgery (SRS) (6 cases, 12%), or endovascular treatment (2 cases, 4%). Patients ≤ 30 years old were more prone to hemorrhagic presentation (OR: 5.23; 95% CI: 1.42-17.19; p = 0.024) and this remained an independent risk factor for rupture after multivariate analysis as well (OR: 4.81; 95% CI: 1.07-21.53; p = 0.040). Following multivariate analysis, the only factor independently associated with poor prognosis in the surgically treated subgroup was a poor clinical status (mRS 3-5) at admission (OR: 96.14; 95% CI: 5.15-1793.9; p = 0.002).

conclusionsManagement of posterior fossa AVMs is challenging, and patients who present with ruptured AVMs often have a poor clinical status at admission leading to a poor prognosis. Therefore, proper and timely management of these patients is essential.

Indexed as

Cranial Fossa, PosteriorIntracranial Arteriovenous MalformationsRadiosurgeryAdolescentAdultChildEndovascular ProceduresFemaleHumansMaleMicrosurgeryMiddle AgedPrognosisRetrospective StudiesTreatment OutcomeYoung AdultClinical outcomePosterior fossa arteriovenous malformationsPrognostic factorsTreatment modalities

Identifiers

PMID38744729
PMCPMC11093870

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.