Evidence map›Paper›PMID 38744530›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2024

Selective Enhancement of REM Sleep in Male Rats through Activation of Melatonin MT

Martha López-Canul, Qianzi He, Tania Sasson, Mohamed Ettaoussi, Danilo De Gregorio, Rafael Ochoa-Sanchez, Helene Catoire, Luca Posa, Guy Rouleau, Jean Martin Beaulieu and 2 more

Abstract read
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Structural and Dynamics Insights into Melatonin Binding to MT1 Receptor.Chembiochem : a European journal of chemical biology · 2026
    Article
  2. Review
  3. Article
  4. Article
  5. Parametric resonance brain model.Scientific reports · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Martha López-CanulNeurobiological Psychiatry Unit, Department of Psychiatry, McGill University, Montreal, Quebec H3A 1A1, Canada.
Qianzi HeNeurobiological Psychiatry Unit, Department of Psychiatry, McGill University, Montreal, Quebec H3A 1A1, Canada.ORCID 0000-0002-4607-166X
Tania SassonNeurobiological Psychiatry Unit, Department of Psychiatry, McGill University, Montreal, Quebec H3A 1A1, Canada.
Mohamed EttaoussiNeurobiological Psychiatry Unit, Department of Psychiatry, McGill University, Montreal, Quebec H3A 1A1, Canada.
Danilo De GregorioNeurobiological Psychiatry Unit, Department of Psychiatry, McGill University, Montreal, Quebec H3A 1A1, Canada.
Rafael Ochoa-SanchezNeurobiological Psychiatry Unit, Department of Psychiatry, McGill University, Montreal, Quebec H3A 1A1, Canada.
Helene CatoireDepartment of Neurology and Neurosurgery, McGill University, Montreal, Quebec H3A 2B4, Canada.
Luca PosaNeurobiological Psychiatry Unit, Department of Psychiatry, McGill University, Montreal, Quebec H3A 1A1, Canada.
Guy RouleauDepartment of Neurology and Neurosurgery, McGill University, Montreal, Quebec H3A 2B4, Canada.
Jean Martin BeaulieuDepartment of Pharmacology and Toxicology, University of Toronto, Toronto, Ontario M5G 2C8, Canada.
Stefano ComaiNeurobiological Psychiatry Unit, Department of Psychiatry, McGill University, Montreal, Quebec H3A 1A1, Canada gabriella.gobbi@mcgill.ca stefano.comai@unipd.it.ORCID 0000-0002-5686-7194
Gabriella GobbiNeurobiological Psychiatry Unit, Department of Psychiatry, McGill University, Montreal, Quebec H3A 1A1, Canada gabriella.gobbi@mcgill.ca stefano.comai@unipd.it.ORCID 0000-0003-4124-9825

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sleep disorders affect millions of people around the world and have a high comorbidity with psychiatric disorders. While current hypnotics mostly increase non-rapid eye movement sleep (NREMS), drugs acting selectively on enhancing rapid eye movement sleep (REMS) are lacking. This polysomnographic study in male rats showed that the first-in-class selective melatonin MT

Indexed as

Locus CoeruleusRats, Sprague-DawleyReceptor, Melatonin, MT1Sleep, REMAdrenergic NeuronsAnimalsMaleNeuronsNorepinephrineRatsNorepinephrineReceptor, Melatonin, MT1EEG/EMGlocus ceruleusmelatonin MT1 receptorsnorepinephrineratsREM sleep

Identifiers

PMID38744530
PMCPMC11255427

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.