ArticleThe Journal of infectious diseases2024
Antibiotic Resistance of Urinary Tract Infection Recurrences in a Large Integrated US Healthcare System.
Article in The Journal of infectious diseases, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
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Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Potential Efficacy of Polyphenols and Isothiocyanates in the Management of Genitourinary Diseases: A Systematic Review of Preclinical and Clinical Studies.International journal of molecular sciences · 2026Pooled it
- Phenotypic Effects of a Small Molecule CpxA Phosphatase Inhibitor on Uropathogenic Escherichia coli.ACS infectious diseases · 2026Article
- Evaluation of a phage-inclusive multimodal strategy for recurrent urinary tract infections.BMC microbiology · 2026Article
- Rising antimicrobial resistance in urinary tract infections in Türkiye: an urgent need for update on regional treatment strategies and for enhanced antimicrobial stewardship efforts.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2026Article
- Therapeutic strategies for multi-resistantJAC-antimicrobial resistance · 2026Review
- Optimizing antimicrobial stewardship in urology: a qualitative study on needs, values and requirements for clinical decision support.Infection prevention in practice · 2026Article
- Overexpression of Escherichia coli yaiX Confers Multidrug Resistance and Enhances Virulence in the Silkworm Infection Model.Microbiology and immunology · 2026Article
- Using electronic health records to assess the relationship between colonization pressure and nosocomial pathogen acquisition.Nature communications · 2026Article
- Epidemiological and Clinical Characteristics Associated with Antimicrobial-Resistant Urinary Tract Infections in Outpatient and Inpatient Settings: A Retrospective Study from Northwestern Mexico.Pathogens (Basel, Switzerland) · 2026Article
- Genomics reveal Staphylococcus aureus persists during long-term urinary catheterization despite antimicrobial therapy and catheter exchanges.Nature communications · 2026Article
- Analysis of Antimicrobial Use and Bacterial Susceptibility in Patients with Urinary Tract Infections at a Certain Hospital From 2021 to 2023: A Retrospective Cohort Study.International journal of general medicine · 2026Article
- Analytical validation of a metagenomic next-generation diagnostic platform for urinary tract infection in a Thai tertiary hospital setting: a BI-Biotia UTI cohort study.Frontiers in cellular and infection microbiology · 2026Article
- Identification of Risk Factors in Patients with Recurrent Cystitis May Improve Individualized Management.Diagnostics (Basel, Switzerland) · 2025Article
- ZoonoticmBio · 2025Article
- Prevalence and economic evaluation of acute uncomplicated cystitis in women from Japan: a retrospective cohort study.JAC-antimicrobial resistance · 2025Article
- The role of Uro-Vaxom in reducing infectious adverse effects and improving outcomes in bacillus Calmette-Guérin therapy for non-muscle-invasive bladder cancer.Investigative and clinical urology · 2025Article
- Effect of host microenvironment and bacterial lifestyles on antimicrobial sensitivity and implications for susceptibility testing.npj antimicrobials and resistance · 2025Review
- Article
- Population Ecology-Quantitative Microbial Risk Assessment (QMRA) Model for Antibiotic-Resistant and SusceptibleEnvironmental science & technology · 2025Article
- New Antimicrobial Materials Based on Plasticized Polyvinyl Chloride for Urinary Catheters: Preparation and Testing.Polymers · 2024Article
Corrections and comments
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Authors and funding
9 authors.
Funding
Abstract
backgroundData on antibiotic resistance of uropathogens for urinary tract infection (UTI) recurrences are lacking.
methodsIn a retrospective cohort of adults at Kaiser Permanente Southern California with culture-confirmed index uncomplicated UTI (uUTI) between January 2016 and December 2020, we examined the number and characteristics of subsequent culture-confirmed UTIs through 2021.
resultsWe identified 148 994 individuals with a culture-confirmed index uUTI (88% female, 44% Hispanic; mean age, 51 years [standard deviation, 19 years]), of whom 19% developed a subsequent culture-confirmed UTI after a median 300 days (interquartile range, 126-627 days). The proportion of UTI due to Escherichia coli was highest for index uUTI (79%) and decreased to 73% for sixth UTI (UTI 6) (P for trend < .001), while the proportion due to Klebsiella spp increased from index UTI (7%) to UTI 6 (11%) (P for trend < .001). Nonsusceptibility to ≥1 and ≥3 antibiotic classes was observed in 57% and 13% of index uUTIs, respectively, and was higher for subsequent UTIs (65% and 20%, respectively, for UTI 6). Most commonly observed antibiotic nonsusceptibility patterns included penicillins alone (12%), and penicillins and trimethoprim-sulfamethoxazole plus ≥1 additional antibiotic class (9%).
conclusionsAntibiotic nonsusceptibility is common in UTIs and increases with subsequent UTIs. Continuous monitoring of UTI recurrences and susceptibility patterns is needed to guide treatment decisions.
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