Evidence map›Paper›PMID 38743622›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2024

A fungal protein organizes both glycogen and cell wall glucans.

Liza Loza, Tamara L Doering

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Liza LozaDepartment of Molecular Microbiology, Washington University in St. Louis School of Medicine, St. Louis, MO 63110.ORCID 0000-0001-6488-451X
Tamara L DoeringDepartment of Molecular Microbiology, Washington University in St. Louis School of Medicine, St. Louis, MO 63110.ORCID 0000-0002-5179-7393

Funding

Rapid production of SARS-CoV-2 molecular clones using CRISPR-based yeast recombineeringR01AI100272 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI MADHANI, HITEN D · 2012 to 2025
$11.3M
CRYPTOCOCCAL GLYCAN SYNTHESISR01AI135012 · NIAID · WASHINGTON UNIVERSITY · PI DOERING, TAMARA L · 2018 to 2022
$2.5M
Filling gaps in the cryptococcal wall with glycogen and a novel enzymeR21AI175875 · NIAID · WASHINGTON UNIVERSITY · PI DOERING, TAMARA L · 2023 to 2024
$428k
Discerning the roles of novel glycosyltransferases in the pathogenic yeast Cryptococcus neoformansF31AI150194 · NIAID · WASHINGTON UNIVERSITY · PI LOZA, LIZA · 2020 to 2022
$96k
HHS | NIH | National Institute of Allergy and Infectious Diseases (NIAID) F31 150194HHS | NIH | National Institute of Allergy and Infectious Diseases (NIAID) R01 135012HHS | NIH | National Institute of Allergy and Infectious Diseases (NIAID) R21 175875NIAID NIH HHS F31 AI150194NIAID NIH HHS R01 AI100272NIAID NIH HHS R01 AI135012NIAID NIH HHS R21 AI175875
6 · The paper itself

Abstract

Glycogen is a glucose storage molecule composed of branched α-1,4-glucan chains, best known as an energy reserve that can be broken down to fuel central metabolism. Because fungal cells have a specialized need for glucose in building cell wall glucans, we investigated whether glycogen is used for this process. For these studies, we focused on the pathogenic yeast

Indexed as

Cell WallCryptococcus neoformansFungal ProteinsGlucansGlycogenbeta-GlucansGlucosyltransferasesbeta-GlucansFungal ProteinsGlucansGlucosyltransferasesGlycogencell wallCryptococcus neoformansglycogenglycogeninglycosyltransferase

Identifiers

PMID38743622
PMCPMC11126952

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.