Evidence map›Paper›PMID 38743437›Full record

ArticleACS sensors2024

Quantum Sensing of Free Radical Generation in Mitochondria of Human Keratinocytes during UVB Exposure.

Siyu Fan, Lluna Lopez Llorens, Felipe P Perona Martinez, Romana Schirhagl

Abstract read
In one paragraph

Article in ACS sensors, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Quantum biology: From mechanisms to medicine.Clinical and translational medicine · 2026
    Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Diamond Chemistry: Advances and Perspectives.Angewandte Chemie (International ed. in English) · 2025
    Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Siyu FanDepartment of Biomaterials & Biomedical Technology, University Medical Center Groningen, University Groningen, Antonius Deusinglaan 1, 9713 AV Groningen, The Netherlands.
Lluna Lopez LlorensDepartment of Biomaterials & Biomedical Technology, University Medical Center Groningen, University Groningen, Antonius Deusinglaan 1, 9713 AV Groningen, The Netherlands.
Felipe P Perona MartinezDepartment of Biomaterials & Biomedical Technology, University Medical Center Groningen, University Groningen, Antonius Deusinglaan 1, 9713 AV Groningen, The Netherlands.ORCID 0000-0001-8759-9586
Romana SchirhaglDepartment of Biomaterials & Biomedical Technology, University Medical Center Groningen, University Groningen, Antonius Deusinglaan 1, 9713 AV Groningen, The Netherlands.ORCID 0000-0002-8749-1054

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ultraviolet (UV) radiation is known to cause skin issues, such as dryness, aging, and even cancer. Among UV rays, UVB stands out for its ability to trigger problems within cells, including mitochondrial dysfunction, oxidative stress, and DNA damage. Free radicals are implicated in these cellular responses, but they are challenging to measure due to their short lifetime and limited diffusion range. In our study, we used a quantum sensing technique (T1 relaxometry) involving fluorescent nanodiamonds (FNDs) that change their optical properties in response to magnetic noise. This allowed us to monitor the free radical presence in real time. To measure radicals near mitochondria, we coated FNDs with antibodies, targeting mitochondrial protein voltage-dependent anion channel 2 (anti-VDAC2). Our findings revealed a dynamic rise in radical levels on the mitochondrial membrane as cells were exposed to UVB (3 J/cm

Indexed as

KeratinocytesMitochondriaUltraviolet RaysFree RadicalsHumansQuantum DotsFree RadicalsdiamondsnanodiamondsNV centersskin cellsUV irradiation

Identifiers

PMID38743437
PMCPMC11129351

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.