Evidence map›Paper›PMID 38743389›Full record

Trial reportEuropean journal of physical and rehabilitation medicine2024

Effects of motor and cognitive complex training on obstacle walking and brain activity in people with Parkinson's disease: a randomized controlled trial.

Pei-Ling Wong, Chen-Wei Hung, Yea-Ru Yang, Nai-Chen Yeh, Shih-Jung Cheng, Ying-Yi Liao, Ray-Yau Wang

Abstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in European journal of physical and rehabilitation medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Pei-Ling WongDepartment of Physical Therapy and Assistive Technology, National Yang Ming Chiao Tung University, Taipei, Taiwan (ROC).
Chen-Wei HungDepartment of Physical Therapy and Assistive Technology, National Yang Ming Chiao Tung University, Taipei, Taiwan (ROC).
Yea-Ru YangDepartment of Physical Therapy and Assistive Technology, National Yang Ming Chiao Tung University, Taipei, Taiwan (ROC).
Nai-Chen YehDepartment of Physical Therapy and Assistive Technology, National Yang Ming Chiao Tung University, Taipei, Taiwan (ROC).
Shih-Jung ChengDepartment of Neurology, Mackay Memorial Hospital, Taipei, Taiwan (ROC).
Ying-Yi LiaoDepartment of Gerontological Health Care, National Taipei University of Nursing and Health Science, Taipei, Taiwan (ROC).
Ray-Yau WangDepartment of Physical Therapy and Assistive Technology, National Yang Ming Chiao Tung University, Taipei, Taiwan (ROC) - rywang@nycu.edu.tw.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe difficulties in obstacle walking are significant in people with Parkinson's disease (PD) leading to an increased fall risk. Effective interventions to improve obstacle walking with possible training-related neuroplasticity changes are needed. We developed two different exercise programs, complex walking training and motor-cognitive training, both challenging motor and cognitive function for people with PD to improve obstacle walking.

aimTo investigate the effects of these two novel training programs on obstacle walking and brain activities in PD.

designA single-center randomized, single-blind controlled study.

settingUniversity laboratory; outpatient. POPULATION: Individuals with idiopathic PD.

methodsThirty-two participants were randomly assigned to the complex walking training group (N.=11), motor-cognitive training group (N.=11) or control group (N.=10). Participants in training groups received exercises for 40 minutes/session, with a total of 12-session over 6 weeks. Control group did not receive additional training. Primary outcomes included obstacle walking, and brain activities (prefrontal cortex (PFC), premotor cortex (PMC), and supplementary motor area (SMA)) during obstacle walking by using functional near-infrared spectroscopy. Secondary outcomes included obstacle crossing, timed up and go test (TUG), cognitive function in different domains, and fall efficacy scale (FES-I).

resultsThe motor-cognitive training group demonstrated greater improvements in obstacle walking speed and stride length, SMA activity, obstacle crossing velocity and stride length, digit span test, and TUG than the control group. The complex walking training did not show significant improvement in obstacle walking or change in brain activation compared with control group. However, the complex walking training resulted in greater improvements in Rey-Osterrieth Complex Figure test, TUG and FES-I compared with the control group.

conclusionsOur 12-session of the cognitive-motor training improved obstacle walking performance with increased SMA activities in people with PD. However, the complex walking training did not lead such beneficial effects as the cognitive-motor training. CLINICAL REHABILITATION IMPACT: The cognitive-motor training is suggested as an effective rehabilitation program to improve obstacle walking ability in individuals with PD.

Indexed as

Exercise TherapyParkinson DiseaseWalkingAgedCognitionFemaleGait Disorders, NeurologicHumansMaleMiddle AgedSingle-Blind MethodSpectroscopy, Near-Infrared

Identifiers

PMID38743389
PMCPMC11391393

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.