Evidence map›Paper›PMID 38743352›Full record

ReviewCurrent cardiology reports2024

Polyvascular Disease: A Narrative Review of Risk Factors, Clinical Outcomes and Treatment.

Manasi Tannu, Connie N Hess, J Antonio Gutierrez, Renato Lopes, Rajesh V Swaminathan, S Elissa Altin, Sunil V Rao

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current cardiology reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
  2. Article
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  6. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Manasi TannuDivision of Cardiology, Duke University Health System, Durham, NC, USA. manasi.tannu@duke.edu.
Connie N HessUniversity of Colorado, School of Medicine and CPC Clinical Research, Aurora, CO, USA.
J Antonio GutierrezDivision of Cardiology, Duke University Health System, Durham, NC, USA.
Renato LopesDivision of Cardiology, Duke University Health System, Durham, NC, USA.
Rajesh V SwaminathanDivision of Cardiology, Duke University Health System, Durham, NC, USA.
S Elissa AltinYale University School of Medicine, New Haven, CT, USA.
Sunil V RaoNYU Langone Health System, New York, NY, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purpose of reviewPolyvascular disease has a significant global burden and is associated with increased risk of major adverse cardiac events with each additional vascular territory involved. The purpose of this review is to highlight the risk factors, associated outcomes, emerging genetic markers, and evidence for screening and treatment of polyvascular disease. RECENT

findingsPolyvascular disease is the presence of atherosclerosis in two or more vascular beds. It has a significant global burden, with a prevalence of 30-70% in patients with known atherosclerosis. Patients with polyvascular disease experience elevated rates of cardiovascular death, myocardial infarction and stroke, especially among high-risk subgroups like those with type 2 diabetes mellitus and there is a step-wise increased risk of adverse outcomes with each additional vascular territory involved. Genetic analyses demonstrate that some individuals may carry a genetic predisposition, while others exhibit higher levels of atherogenic lipoproteins and inflammatory markers. Routine screening for asymptomatic disease is not currently recommended by major cardiovascular societies unless patients are high-risk. While there are no established protocols for escalating treatment, existing guidelines advocate for lipid-lowering therapy. Additionally, recent studies have demonstrated benefit from antithrombotic agents, such as P2Y

Indexed as

Diabetes Mellitus, Type 2AtherosclerosisCardiovascular DiseasesGenetic Predisposition to DiseaseHumansPrevalenceRisk FactorsBleeding riskCerebrovascular diseaseCoronary artery diseaseHigh-risk cardiovascular diseasePeripheral artery diseasePolyvascular disease

Identifiers

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.