Evidence map›Paper›PMID 38743265›Full record

Trial reportInternational journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group2024

Feasibility and acceptability of an integrated mind-body intervention for depression: whole-body hyperthermia (WBH) and cognitive behavioral therapy (CBT).

Ashley E Mason, Anoushka Chowdhary, Wendy Hartogensis, Chelsea J Siwik, Osnat Lupesko-Persky, Leena S Pandya, Stefanie Roberts, Claudine Anglo, Patricia J Moran, J Craig Nelson and 4 more

3 registry-linked trialsAbstract readClinical Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05041361 nacompletednot on this map

HypErthermia as an Additional Treatment for the Biology and Experience of Depression: The HEATBED Study

TypeinterventionalSponsorUniversity of California, San FranciscoRan2021 to 2023Enrolled16ConditionsMajor Depressive DisorderArmsCognitive Behavioral Therapy (CBT), Whole-Body Hyperthermia (WBH)
NCT07564440 naenrolling by invitationnot on this mapstarted 2026, after this paper: background citation

Clinical and Biological Safety Study of the BTT Hyperthermia in Adult Subjects

TypeinterventionalSponsorMarc AbreuRan2026 to 2026Enrolled20ConditionsSafety StudyArmsHyperthermia
NCT07596914 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

Assessing Multi-site Feasibility of an Integrated Whole-body Hyperthermia and Behavioral Intervention for Major Depressive Disorder: The MULTIBED Study

TypeinterventionalSponsorUniversity of California, San FranciscoRan2026 to 2029Enrolled60ConditionsMajor Depressive DisorderArmsCognitive Behavioral Therapy (CBT), Whole-Body Hyperthermia
3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Ashley E MasonOsher Center for Integrative Health, University of California San Francisco (UCSF), San Francisco, CA, USA.
Anoushka ChowdharyDepartment of Psychology, University of Arizona, Tucson, AZ, USA.
Wendy HartogensisOsher Center for Integrative Health, University of California San Francisco (UCSF), San Francisco, CA, USA.
Chelsea J SiwikDepartment of Wellness and Preventive Medicine, Cleveland Clinic, Cleveland, OH, USA.
Osnat Lupesko-PerskyOsher Center for Integrative Health, University of California San Francisco (UCSF), San Francisco, CA, USA.
Leena S PandyaOsher Center for Integrative Health, University of California San Francisco (UCSF), San Francisco, CA, USA.
Stefanie RobertsOsher Center for Integrative Health, University of California San Francisco (UCSF), San Francisco, CA, USA.
Claudine AngloOsher Center for Integrative Health, University of California San Francisco (UCSF), San Francisco, CA, USA.
Patricia J MoranOsher Center for Integrative Health, University of California San Francisco (UCSF), San Francisco, CA, USA.
J Craig NelsonWeill Institute for Neurosciences, University of California San Francisco (UCSF), San Francisco, CA, USA.
Christopher A LowryDepartment of Integrative Physiology, University of Colorado Boulder, Boulder, CO, USA.
Rhonda P PatrickFoundMyFitness, LLC, San Diego, CA, USA.
Charles L RaisonDepartment of Psychiatry, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI, USA.
Frederick M HechtOsher Center for Integrative Health, University of California San Francisco (UCSF), San Francisco, CA, USA.

Funding

Optimizing an integrated whole-body hyperthermia and behavioral intervention for major depressive disorderR34AT011221 · NCCIH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI HECHT, FREDERICK M, MASON, ASHLEY E. · 2021 to 2023
$727k
NCCIH NIH HHS R34 AT011221
6 · The paper itself

Abstract

objectiveTo examine the feasibility of an integrated mind-body MDD treatment combining cognitive behavioral therapy (CBT) and whole-body hyperthermia (WBH).

methodsIn this single-arm trial, 16 adults with MDD initially received 8 weekly CBT sessions and 8 weekly WBH sessions. Outcomes included WBH sessions completed (primary), self-report depression assessments completed (secondary), and pre-post intervention changes in depression symptoms (secondary). We also explored changes in mood and cognitive processes and assessed changes in mood as predictors of overall treatment response.

resultsThirteen participants (81.3%) completed LIMITATIONS: Small sample size and single-arm design limit generalizability.

conclusionAn integrated mind-body intervention comprising weekly CBT sessions and bi-weekly WBH sessions was feasible. Results warrant future larger controlled clinical trials.

Indexed as

Cognitive Behavioral TherapyHyperthermia, InducedAdultDepressionFeasibility StudiesFemaleHumansMaleMiddle AgedMind-Body Therapiesacceptabilitybody temperaturedepressionfeasibilityWhole-body hyperthermia

Identifiers

PMID38743265
PMCPMC11216717

What OpenQuestion holds

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Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.