Evidence map›Paper›PMID 38743241›Full record

ArticleAdvances in therapy2024

Early Therapeutic Drug Monitoring Optimizes Teicoplanin Use in Febrile Neutropenic Patients with Hematological Malignancies.

Yu-Wen Wang, Hsin-An Hou, Chien-Chin Lin, Hsing-Yu Lin, Pin-Zi Chen, Ching-Hua Kuo, Huai-Hsuan Chiu, Chia-Chi Chuang, Yi-Jing Chen, Shu-Wen Lin

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Article in Advances in therapy, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Yu-Wen WangDepartment of Pharmacy, National Taiwan University Hospital, Taipei, Taiwan.ORCID 0009-0002-0573-2238
Hsin-An HouDivision of Hematology, Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.
Chien-Chin LinDivision of Hematology, Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.
Hsing-Yu LinDepartment of Pharmacy, National Taiwan University Hospital, Taipei, Taiwan.
Pin-Zi ChenDepartment of Pharmacy, National Taiwan University Hospital, Taipei, Taiwan.
Ching-Hua KuoSchool of Pharmacy, College of Medicine, National Taiwan University, 33, Linsen S. Rd, Room 216, Taipei, Taiwan.
Huai-Hsuan ChiuSchool of Pharmacy, College of Medicine, National Taiwan University, 33, Linsen S. Rd, Room 216, Taipei, Taiwan.
Chia-Chi ChuangSchool of Pharmacy, College of Medicine, National Taiwan University, 33, Linsen S. Rd, Room 216, Taipei, Taiwan.
Yi-Jing ChenGraduate Institute of Clinical Pharmacy, National Taiwan University, Taipei, Taiwan.
Shu-Wen LinSchool of Pharmacy, College of Medicine, National Taiwan University, 33, Linsen S. Rd, Room 216, Taipei, Taiwan. shuwenlin@ntu.edu.tw.

Funding

National Taiwan University Hospital 108-S4335
6 · The paper itself

Abstract

introductionA target trough concentration (C

methodsThis single-center, prospective study enrolled patients with hematological malignancies who were treated with teicoplanin either as an empirical antibiotic for FN or as targeted treatment for Gram-positive bacteria. Blood samples were collected on day three (48 h) post-loading doses, day 5 (96 h), and day 8 (when applicable) and determined by ultrahigh-pressure liquid chromatography-triple quadruple mass spectrometry. A total of 117 samples from 47 patients with FN (27 men, 20 women) were consecutively analyzed. A two-tailed α value of 0.05 was considered statistically significant.

resultsThe mean C

conclusionsThe C

Indexed as

Anti-Bacterial AgentsDrug MonitoringFebrile NeutropeniaHematologic NeoplasmsTeicoplaninAdultAgedDose-Response Relationship, DrugFemaleHumansMaleMiddle AgedProspective StudiesTreatment OutcomeYoung AdultAnti-Bacterial AgentsTeicoplaninFebrile neutropeniaHematological malignanciesTeicoplaninTherapeutic drug monitoring

Identifiers

PMID38743241

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.