Evidence map›Paper›PMID 38743231›Full record

ArticleMethods in molecular biology (Clifton, N.J.)2024

Direct Analysis of HIV mRNA m

Ethan Honeycutt, Fredrick Kizito, Jonathan Karn, Thomas Sweet

Abstract read
In one paragraph

Article in Methods in molecular biology (Clifton, N.J.), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. When animal viruses meet NVeterinary research · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ethan HoneycuttDepartment of Molecular Biology and Microbiology, School of Medicine, Case Western Reserve University, Cleveland, OH, USA.
Fredrick KizitoDepartment of Molecular Biology and Microbiology, School of Medicine, Case Western Reserve University, Cleveland, OH, USA.
Jonathan KarnDepartment of Molecular Biology and Microbiology, School of Medicine, Case Western Reserve University, Cleveland, OH, USA. jonathan.karn@case.edu.ORCID 0000-0002-2900-094X
Thomas SweetDepartment of Nutrition, School of Medicine, Case Western Reserve University, Cleveland, OH, USA.

Funding

m6A Modification of HIV RNA Affects its Post-transcriptional ProcessingF31AI183967 · NIAID · CASE WESTERN RESERVE UNIVERSITY · PI HONEYCUTT, ETHAN · 2024 to 2025
$99k
NIAID NIH HHS F31 AI183967
6 · The paper itself

Abstract

The post-transcriptional processing and chemical modification of HIV RNA are understudied aspects of HIV virology, primarily due to the limited ability to accurately map and quantify RNA modifications. Modification-specific antibodies or modification-sensitive endonucleases coupled with short-read RNA sequencing technologies have allowed for low-resolution or limited mapping of important regulatory modifications of HIV RNA such as N

Indexed as

AdenosineNanopore SequencingRNA, MessengerRNA, ViralHigh-Throughput Nucleotide SequencingHIVHIV-1HIV InfectionsHumansMethylationRNA Processing, Post-TranscriptionalSequence Analysis, RNAAdenosineRNA, MessengerRNA, ViralDirect RNA sequencingN6-methyladenosineOxford nanopore sequencing

Identifiers

PMID38743231
PMCPMC12120845

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.