ArticleOphthalmology and therapy2024
Assessment of OCT-Based Macular Curvature and Its Relationship with Macular Microvasculature in Children with Anisomyopia.
Article in Ophthalmology and therapy, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed.
- Differences in Posterior Ocular Morphology Following Red Light Therapy Versus 0.01% Atropine for Myopia Control: A Randomized Controlled Trial Analysis.Investigative ophthalmology & visual science · 2026Trial
- Motion-corrected Gaussian, mean, and parametric curvature mapping of the posterior eye with pupil-tracked whole-eye OCT.Biomedical optics express · 2026Article
- Macular Curvature in Children Born Preterm With and Without ROP - Results From the Gutenberg Prematurity Study Young.Investigative ophthalmology & visual science · 2026Article
- Regional choroidal perfusion deficits and vector-based choroidal associations in adolescent astigmatism.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026Article
- Longitudinal changes in macular curvature and axial elongation in school children.International journal of retina and vitreous · 2025Article
- Longitudinal Study of Changes in Retinal Curvature and its Relationship With Myopia Shift in Chinese Children.Investigative ophthalmology & visual science · 2025Article
- Interocular Differences in Retinal Curvature in Anisometropic Patients and Their Association With Myopic Degree Differences.Investigative ophthalmology & visual science · 2025Article
- Relationship between the morphology of the posterior pole of the eyeball and changes in choroidal structure and blood flow in myopia.Quantitative imaging in medicine and surgery · 2024Article
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9 authors.
Funding
Abstract
introductionTo evaluate the intraocular differences in optical coherence tomography (OCT)-based macular curvature index (MCI) among children with anisomyopia and to investigate the relationship between MCI and the macular microvasculature.
methodsFifty-two schoolchildren with anisometropia > 2.00 D were enrolled and underwent comprehensive examinations including cycloplegic refraction, axial length (AL), and swept source OCT/OCT angiography. OCT-based MCIs were determined from horizontal and vertical B-scans by a customized curve fitting model in MATLAB R2022 at 1-mm-, 3-mm-, and 6-mm-diameter circles at fovea. Characteristics and topographic variation of MCI was analyzed, and the relationships with microvascularity and its associated factors were investigated.
resultsMCI achieved high reliability and repeatability. There were overall larger MCIs in the more myopic eyes than the less myopic eyes in 1-mm-, 3-mm-, and 6-mm-diameter circles at fovea (all p < 0.001). For the topographic variation, horizontal MCI was significantly greater than vertical MCI (all p < 0.001), and was the largest in 6-mm circle, followed by 3-mm and 1-mm circles. Stronger correlation of horizontal MCI with myopic severity than vertical MCI was found. Partial Pearson's correlation found MCI was negatively associated with deep capillary plexus (DCP) vessel density (p = 0.016). Eyes with a higher MCI in a 6-mm circle were more likely to have longer AL (p < 0.001), lower DCP vessel density (p = 0.037), and thinner choroidal thickness (ChT) (p = 0.045).
conclusionLarger MCI was found in the more myopic eyes of children with anisomyopia and was significantly associated with smaller DCP density, suggesting that MCI was an important indicator of myopia-related retinal microvascularity change, and it could be a valuable metric for myopia assessment in children.
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