Evidence map›Paper›PMID 38743080›Full record

ArticleEuropean archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery2024

Heated humidified high-flow nasal cannula: a new conservative approach for neonatal nasal stenosis.

Shany Havazelet, Patrick Stafler, Ihab Zarzur, Tara Coreanu, Roy Hod, Keren Armoni-Domany, Dror Gilony

Abstract read
In one paragraph

Article in European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Shany Havazelet *Department of Otolaryngology - Head and Neck Surgery, Rabin Medical Center, Petach Tikva, Israel. shany.havazelet@gmail.com.ORCID http://orcid.org/0009-0009-9435-374X
Patrick Stafler *Institute of Pediatric Pulmonology, Schneider Children's Medical Center of Israel, Petach Tikva, Israel.
Ihab ZarzurInstitute of Pediatric Pulmonology, Schneider Children's Medical Center of Israel, Petach Tikva, Israel.
Tara CoreanuDepartment of Otolaryngology - Head and Neck Surgery, Rabin Medical Center, Petach Tikva, Israel.
Roy HodDepartment of Pediatric Otolaryngology, Schneider Children's Medical Center of Israel, Petach Tikva, Israel.
Keren Armoni-DomanyFaculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
Dror GilonyDepartment of Pediatric Otolaryngology, Schneider Children's Medical Center of Israel, Petach Tikva, Israel.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe aim of this study is to evaluate the efficacy of heated humidified high flow nasal cannula (HFNC) therapy as a conservative treatment option for newborns suffering from nasal stenosis, a condition that often leads to respiratory distress and feeding difficulties. Given the increasing utilization of HFNC in various upper and lower respiratory tract indications, characterized by its flow-based mechanism and minimal mucosal damage, we seek to investigate its potential benefits in this specific patient population.

methodsA retrospective chart review of newborns with congenital nasal stenosis treated with HFNC for respiratory distress or feeding difficulties in a pediatric tertiary center between 2014 and 2022. Data were collected for demographic characteristics, clinical presentation and ventilatory requirements, pre and post HFNC application.

resultsSix infants with nasal stenosis were included in the study cohort. Five were diagnosed with congenital pyriform aperture stenosis, three of whom had additional midnasal stenosis. One patient had nasal synechiae. Two patients had failed surgical treatment and all patients failed conservative treatment prior to HFNC treatment. Following HFNC use, improvement was noted in oxygen saturations, heart and respiratory rates, meal volumes and weight. None of the patients required any additional sinonasal surgical treatment. No complications were observed.

conclusionsIn this case series, we present the first documented use of HFNC treatment for nasal stenosis, showing favorable results. Further studies with a larger cohort, wider range of conditions and extended follow-up periods are needed to establish the risks and benefits of HFNC for neonatal nasal stenosis.

Indexed as

CannulaNasal ObstructionOxygen Inhalation TherapyConservative TreatmentConstriction, PathologicFemaleHot TemperatureHumansHumidityInfant, NewbornMaleRetrospective StudiesTreatment OutcomeCongenital pyriform aperture stenosisHeated humidified high-flow nasal cannula (HFNC)Nasal stenosisPediatric respiratory managementSinonasal surgical treatment

Identifiers

PMID38743080
PMCPMC11416382

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.