ArticleInternational braz j urol : official journal of the Brazilian Society of Urology
Evaluating the Safety of Retrograde Intrarenal Surgery (RIRS): Intra- and Early Postoperative Complications in Patients Enrolled in the Global Multicentre Flexible Ureteroscopy Outcome Registry (FLEXOR).
Article in International braz j urol : official journal of the Brazilian Society of Urology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.
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25 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Pooled it
- Article
- Outcomes of suction mini-percutaneous nephrolithotomy using disposable versus reusable sheaths: Real-world observations and inferences from the Suction Technology Utility in Mini-Percutaneous nephrolithotomy Study (STUMPS) registry.Asian journal of urology · 2026Article
- Outpatient versus inpatient flexible ureteroscopy with flexible and navigable suction access sheath: A multicenter comparative analysis of perioperative outcomes from the flexible and navigable access sheath collaborative study group.Asian journal of urology · 2026Article
- FANS-UAS-assisted RIRS under local anesthesia: promising results, but are we ready for definitive conclusions?International journal of surgery (London, England) · 2026Article
- Article
- Retrograde Intrarenal Renal Surgery versus Supine Mini Percutaneous Nephrolithotripsy in Treatment of Renal Pelvic Stones Less than 2 cm, Randomized Clinical Study.Urology research & practice · 2026Article
- Can We Avoid Radiation Exposure in Retrograde Intrarenal Surgery?Medicina (Kaunas, Lithuania) · 2026Article
- Safety and Efficacy of Flexible Ureteroscopy for Renal Stone Disease in Elderly Patients: A Scoping Review.Journal of clinical medicine · 2026Review
- Elective flexible ureteroscopy with suction sheaths for infectious stones in prior UTI patients.BJUI compass · 2026Article
- Development and validation of an interpretable machine learning model for predicting postoperative fever after flexible ureteroscopic lithotripsy: a single-center retrospective cohort study.Frontiers in medicine · 2026Article
- Innersight, a novel software for the formation of preoperative CT-based 3D models for the treatment of lithiasis: does it really help? A pilot study.World journal of urology · 2025Article
- Lasing strategy and its influence on 30-day operative outcomes in flexible ureteroscopy with FANS: inferences from a real-world prospective multicenter study by EAU-endourology and AUSET.World journal of urology · 2025Article
- Construction and validation of a nomogram to predict urosepsis in patients with symptomatic ureterolithiasis after ureteroscopic lithotripsy.Urolithiasis · 2025Article
- Single-use versus reusable flexible ureterorenoscopes with FANS: a multicenter propensity-matched analysis of outcomes in a large series from the EAU-Endourology Section and FANS Collaborative Group.World journal of urology · 2025Article
- Flexible ureteroscopy for renal stones comparing non suction conventional UAS vs flexible and navigable suction ureteral access sheaths in a multicenter real-world experience. Is it finally time to bury the no suction ureteral access sheath? An EAU endourology analysis.World journal of urology · 2025Article
- Clinical characteristics and risk factors analysis of bilateral renal tuberculosis.International urology and nephrology · 2025Article
- Analysis of risk factors for urinary tract infection and bleeding after retrograde flexible ureteroscopy for stone removal.Frontiers in surgery · 2025Article
- International Brazilian Journal of Urology highlights experimental studies in Infertility in this number.International braz j urol : official journal of the Brazilian Society of UrologyArticle
- Quality of Life in Patients with Ureteral Stones: Translation and Validation of the Brazilian Version of the Cambridge Ureteral Stone PROM (Br-CUSP).International braz j urol : official journal of the Brazilian Society of UrologyArticle
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19 authors.
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No grant is acknowledged in the PubMed record.
Abstract
purposeTo assess the incidence of the most common intra- and early postoperative complications following RIRS in a large series of patients with kidney stones.
methodsWe conducted a retrospective analysis of patients with kidney stones who underwent RIRS across 21 centers from January 2018 to August 2021, as part of the Global Multicenter Flexible Ureteroscopy Outcome (FLEXOR) Registry.
resultsAmong 6669 patients undergoing RIRS, 4.5% experienced intraoperative pelvicalyceal system bleeding without necessitating blood transfusion. Only 0.1% of patients, required a blood transfusion. The second most frequent intraoperative complication was ureteric injury due to the ureteral access sheath requiring stenting (1.8% of patients). Postoperatively, the most prevalent early complications were fever/infections requiring antibiotics (6.3%), blood transfusions (5.5%), and sepsis necessitating intensive care unit admission (1.3%). In cases of ureteric injury, a notably higher percentage of patients exhibited multiple stones and stone(s) in the lower pole, and these cases were correlated with prolonged lasing and overall surgical time. Hematuria requiring a blood transfusion was associated with an increased prevalence of larger median maximum stone diameters, particularly among patients with stones exceeding 20 mm. Furthermore, these cases exhibited a significant prolongation in surgical time. Sepsis necessitating admission to the intensive care unit was more prevalent among the elderly, concomitant with a significantly larger median maximum stone diameter.
conclusionsOur analysis showed that RIRS has a good safety profile but bleeding requiring transfusions, ureteric injury, fever, and sepsis are still the most common complications despite advancements in technology.
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