Evidence map›Paper›PMID 38742901›Full record

ArticleJournal of virology2024

Optimization of quenched fluorescent peptide substrates of SARS-CoV-2 3CL

Hugo Cesar Ramos de Jesus, Nestor Solis, Yoan Machado, Isabel Pablos, Peter A Bell, Reinhild Kappelhoff, Peter M Grin, Carlos A Sorgi, Georgina S Butler, Christopher M Overall

Abstract read
In one paragraph

Article in Journal of virology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Molecular insights into NLRP1 Gly/N-degron recognition by CRL2Acta crystallographica. Section F, Structural biology communications · 2026
    Article
  2. Review
  3. Article
  4. The main protease (MCommunications biology · 2025
    Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Hugo Cesar Ramos de Jesus *Centre for Blood Research, Life Sciences Centre, University of British Columbia, Vancouver, British Columbia, Canada.ORCID 0000-0001-8223-094X
Nestor Solis *Centre for Blood Research, Life Sciences Centre, University of British Columbia, Vancouver, British Columbia, Canada.ORCID 0000-0002-8208-0352
Yoan MachadoCentre for Blood Research, Life Sciences Centre, University of British Columbia, Vancouver, British Columbia, Canada.ORCID 0000-0002-8251-3744
Isabel PablosCentre for Blood Research, Life Sciences Centre, University of British Columbia, Vancouver, British Columbia, Canada.ORCID 0000-0001-8052-3853
Peter A BellCentre for Blood Research, Life Sciences Centre, University of British Columbia, Vancouver, British Columbia, Canada.ORCID 0000-0001-6143-5444
Reinhild KappelhoffCentre for Blood Research, Life Sciences Centre, University of British Columbia, Vancouver, British Columbia, Canada.ORCID 0000-0001-9810-7751
Peter M GrinCentre for Blood Research, Life Sciences Centre, University of British Columbia, Vancouver, British Columbia, Canada.ORCID 0000-0001-9504-9664
Carlos A SorgiCentre for Blood Research, Life Sciences Centre, University of British Columbia, Vancouver, British Columbia, Canada.ORCID 0000-0001-7528-9935
Georgina S ButlerCentre for Blood Research, Life Sciences Centre, University of British Columbia, Vancouver, British Columbia, Canada.ORCID 0000-0003-1172-1578
Christopher M OverallCentre for Blood Research, Life Sciences Centre, University of British Columbia, Vancouver, British Columbia, Canada.ORCID 0000-0001-5844-2731

Funding

Canadian Government | Canadian Institutes of Health Research (CIHR) 148408
6 · The paper itself

Abstract

SARS-CoV-2 3C-like main protease (3CL

Indexed as

Coronavirus 3C ProteasesProteomicsSARS-CoV-2Catalytic DomainCOVID-19HumansMolecular Docking SimulationPeptidesSubstrate Specificity3C-like proteinase, SARS-CoV-2Coronavirus 3C ProteasesPeptides3CLpro main proteaseCOVID-19Mprooxidised methioninepeptide assaysPICSproteomicsP' sideSARS-CoV-2structure activity relationship

Identifiers

PMID38742901
PMCPMC11237654

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.