Evidence map›Paper›PMID 38742896›Full record

ArticleAntimicrobial agents and chemotherapy2024

Safety, pharmacokinetics, and potential neurological interactions of ivermectin, tafenoquine, and chloroquine in Rhesus macaques.

Pattaraporn Vanachayangkul, Chanikarn Kodchakorn, Winita Ta-Aksorn, Rawiwan Im-Erbsin, Anchalee Tungtaeng, Phornpimon Tipthara, Joel Tarning, Luis A Lugo-Roman, Mariusz Wojnarski, Brian A Vesely and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Pattaraporn VanachayangkulDepartment of Bacterial and Parasitic Diseases, Armed Forces Research Institute of Medical Sciences, Bangkok, Thailand.
Chanikarn KodchakornDepartment of Bacterial and Parasitic Diseases, Armed Forces Research Institute of Medical Sciences, Bangkok, Thailand.
Winita Ta-AksornDepartment of Bacterial and Parasitic Diseases, Armed Forces Research Institute of Medical Sciences, Bangkok, Thailand.
Rawiwan Im-ErbsinDepartment of Veterinary Medicine, Armed Forces Research Institute of Medical Sciences, Bangkok, Thailand.
Anchalee TungtaengDepartment of Veterinary Medicine, Armed Forces Research Institute of Medical Sciences, Bangkok, Thailand.
Phornpimon TiptharaMahidol Oxford Tropical Medicine Research Unit, Mahidol University, Bangkok, Thailand.
Joel TarningMahidol Oxford Tropical Medicine Research Unit, Mahidol University, Bangkok, Thailand.ORCID 0000-0003-4566-4030
Luis A Lugo-RomanDepartment of Veterinary Medicine, Armed Forces Research Institute of Medical Sciences, Bangkok, Thailand.
Mariusz WojnarskiDepartment of Bacterial and Parasitic Diseases, Armed Forces Research Institute of Medical Sciences, Bangkok, Thailand.
Brian A VeselyDepartment of Bacterial and Parasitic Diseases, Armed Forces Research Institute of Medical Sciences, Bangkok, Thailand.
Kevin C KobylinskiMahidol Oxford Tropical Medicine Research Unit, Mahidol University, Bangkok, Thailand.ORCID 0000-0002-4807-9681

Funding

US Military Infectious Disease Research Program
6 · The paper itself

Abstract

Ivermectin (IVM) could be used for malaria control as treated individuals are lethal to blood-feeding

Indexed as

AminoquinolinesAntimalarialsChloroquineDrug InteractionsIvermectinMacaca mulattaAnimalsATP Binding Cassette Transporter, Subfamily B, Member 1Blood-Brain BarrierFemaleMaleAminoquinolinesAntimalarialsATP Binding Cassette Transporter, Subfamily B, Member 1ChloroquineIvermectintafenoquinechloroquineivermectinmacaquepharmacokineticssafetytafenoquine

Identifiers

PMID38742896
PMCPMC11620492

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.