Evidence map›Paper›PMID 38742892›Full record

ArticlemSystems2024

Metatranscriptomic investigation of single

Calla Martyn, Beth M Hayes, Domokos Lauko, Edward Midthun, Gloria Castaneda, Angela Bosco-Lauth, Daniel J Salkeld, Amy Kistler, Katherine S Pollard, Seemay Chou

Abstract read
In one paragraph

Article in mSystems, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Metagenomic Analysis of Tick-Borne Viruses Associated WithTransboundary and emerging diseases · 2025
    Article
  6. A virus associated with the zoonotic pathogenbioRxiv : the preprint server for biology · 2024
    Article
  7. Shotgun Metagenomics Reveals Minor Micro"International journal of molecular sciences · 2024
    Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Calla MartynDepartment of Biochemistry & Biophysics, University of California-San Francisco, San Francisco, California, USA.ORCID 0000-0002-1886-5198
Beth M HayesDepartment of Biochemistry & Biophysics, University of California-San Francisco, San Francisco, California, USA.
Domokos LaukoDepartment of Biochemistry & Biophysics, University of California-San Francisco, San Francisco, California, USA.
Edward MidthunDepartment of Biomedical Sciences, Colorado State University-Fort Collins, Fort Collins, Colorado, USA.
Gloria CastanedaChan Zuckerberg Biohub, San Francisco, San Francisco, California, USA.
Angela Bosco-LauthDepartment of Biomedical Sciences, Colorado State University-Fort Collins, Fort Collins, Colorado, USA.
Daniel J SalkeldDepartment of Biology, Colorado State University-Fort Collins, Fort Collins, Colorado, USA.
Amy KistlerChan Zuckerberg Biohub, San Francisco, San Francisco, California, USA.ORCID 0000-0003-1112-719X
Katherine S PollardGladstone Institute of Data Science & Biotechnology, San Francisco, California, USA.ORCID 0000-0002-9870-6196
Seemay ChouDepartment of Biochemistry & Biophysics, University of California-San Francisco, San Francisco, California, USA.ORCID 0000-0002-7271-303X

Funding

PHOSPHORYLATED ISONUCLEOSIDES: NEW ANTI-HIV AGENTSR01AI032851 · NIAID · UNIVERSITY OF IOWA · PI NAIR, VASU · 1992 to 2003
$709k
Chan Zuckerberg BiohubGladstone Institutes (J. David Gladstone Institutes)HHS | National Institutes of Health (NIH) R01 AI32851NIAID NIH HHS R01 AI032851Pew Charitable Trusts (PCT)
6 · The paper itself

Abstract

Ticks are increasingly important vectors of human and agricultural diseases. While many studies have focused on tick-borne bacteria, far less is known about tick-associated viruses and their roles in public health or tick physiology. To address this, we investigated patterns of bacterial and viral communities across two field populations of western black-legged ticks ( IMPORTANCE: Ticks are increasingly important vectors of disease, particularly in the United States where expanding tick ranges and intrusion into previously wild areas has resulted in increasing human exposure to ticks. Emerging human pathogens have been identified in ticks at an increasing rate, and yet little is known about the full community of microbes circulating in various tick species, a crucial first step to understanding how they interact with each and their tick host, as well as their ability to cause disease in humans. We investigated the bacterial and viral communities of the Western blacklegged tick in California and found 11 previously uncharacterized viruses circulating in this population.

Indexed as

IxodesAnimalsBacteriaGenome, ViralMicrobiotaRNA, MessengerRNA VirusesTranscriptomeRNA, Messengerarthropod vectorsbioinformaticsendosymbiontsinnate immunitymetagenomicsmetatranscriptomicsnonhuman microbiomevector-borne disease

Identifiers

PMID38742892
PMCPMC11237458

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.