ArticleClinical infectious diseases : an official publication of the Infectious Diseases Society of America2024
High Prevalence of Unconfirmed Positive HIV Polymerase Chain Reaction Test Results Among African Infants With HIV Exposure in the International Epidemiology Databases to Evaluate AIDS Consortium.
James G Carlucci, Thomas Huntington, Karl-Günter Technau, Marcel Yotebieng, Valériane Leroy, Kim Anderson, Madeleine Amorissani-Folquet, Kara Wools-Kaloustian, Andrew Edmonds
Abstract read
In one paragraphArticle in Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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2 · The registryThe trial behind it
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4 · The recordCorrections and comments
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5 · Who and what moneyAuthors and funding
9 authors.
James G CarlucciDepartment of Pediatrics, Indiana University School of Medicine, Indianapolis, Indiana, USA.ORCID 0000-0002-3969-8544 Thomas HuntingtonIndiana University School of Medicine, Indianapolis, Indiana, USA.
Karl-Günter TechnauDepartment of Paediatrics and Child Health, Faculty of Health Sciences, Empilweni Services and Research Unit, Rahima Moosa Mother and Child Hospital, University of the Witwatersrand, Johannesburg, South Africa.
Marcel YotebiengDepartment of Medicine, Albert Einstein College of Medicine, New York, New York, USA.
Valériane LeroyCERPOP, SPHERE, Inserm, University of Toulouse, Toulouse, France.
Kim AndersonFaculty of Health Sciences, Centre for Infectious Disease Epidemiology and Research, School of Public Health, University of Cape Town, Cape Town, South Africa.
Madeleine Amorissani-FolquetDepartment of Pediatrics, University Houphouet-Boigny, Abidjan, Côte d'Ivoire.
Kara Wools-KaloustianDepartment of Medicine, Indiana University School of Medicine, Indianapolis, Indiana, USA.
Andrew EdmondsDepartment of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
Funding
East Africa International Epidemiology Database to evaluate AIDS (IeDEA) Regional ConsortiumU01AI069911 · NIAID · INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS · PI AGGREY SEMWENDERO SEMEERE, Kara Kay Wools-Kaloustian · 2006 to 2026
$57.7MObservational Antiretroviral Studies In Southern Africa (OASIS) CollaborationU01AI069924 · NIAID · UNIVERSITAT BERN · PI Cleophas Chimbetete, Mary-Ann Davies · 2006 to 2026
$55.9M"Enhancing Cancer Research in Central Africa IeDEA"U01AI096299 · NIAID · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI Denis Nash, Marcel Yotebieng · 2011 to 2026
$35.8MWADA (West Africa Database on Antiretroviral Therapy) CollaborationU01AI069919 · NIAID · UNIVERSITY OF BORDEAUX II · PI Didier Koumavi Ekouevi, Antoine Jaquet · 2006 to 2026
$29.9MNeuro HPA Project 1U54AG062334 · NIA · EMORY UNIVERSITY · PI Cecile Delille Lahiri, Vasiliki Michopoulos · 2018 to 2026
$12.2MLong term outcomes of therapy in women initiated on lifelong ART because of pregnancy in DR CongoR01HD087993 · NICHD · OHIO STATE UNIVERSITY · PI BABAKAZO, PELAGIE DIAMBALULA, YOTEBIENG, MARCEL · 2016 to 2020
$3.1MDeveloping an enhanced Mentor Mother strategy to improve prevention of mother-to-child transmission of HIV (PMTCT) outcomesK23HD109056 · NICHD · INDIANA UNIVERSITY INDIANAPOLIS · PI JAMES G CARLUCCI · 2022 to 2026
$772kEunice Kennedy Shriver National Institute of Child Health and Human Development K23HD109056FIC NIH HHS U01AI096299National Institute of Allergy and Infectious DiseasesNCI NIH HHSNHLBI NIH HHSNIAAA NIH HHSNIAID NIH HHS U01 AI069911NIAID NIH HHS U01 AI069919NIAID NIH HHS U01 AI069924NIAID NIH HHS U01 AI096299NIA NIH HHS U54 AG062334NICHD NIH HHS K23 HD109056NICHD NIH HHS R01 HD087993NIDA NIH HHSNIDDK NIH HHSNIH HHSNIMH NIH HHS
6 · The paper itselfAbstract
In a large, multiregional cohort of African infants with human immunodeficiency virus (HIV) exposure, 44% of those with a positive HIV polymerase chain reaction test lacked a confirmatory positive test. Efforts are needed to ensure high-fidelity implementation of HIV testing algorithms so that all positive results are confirmed.
Indexed as
HIV InfectionsAfricaCohort StudiesFemaleHIV TestingHumansInfantInfant, NewbornInfectious Disease Transmission, VerticalMalePolymerase Chain ReactionPrevalenceAfricaconfirmatory testingHIVinfantpolymerase chain reaction
Identifiers
PMID38742844
PMCPMC11650864
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