Evidence map›Paper›PMID 38742701›Full record

ArticleAmerican journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists2024

The times are changing: A primer on novel clinical trial designs and endpoints in critical care research.

Michael L Behal, Alexander H Flannery, Todd A Miano

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Michael L BehalDepartment of Pharmacy, University of Tennessee Medical Center, Knoxville, TN, USA.
Alexander H FlanneryDepartment of Pharmacy Practice and Science, University of Kentucky College of Pharmacy, Lexington, KY, USA.
Todd A MianoDepartment of Biostatistics, Epidemiology, and Informatics, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, and Department of Pharmacy, Hospital of the University of Pennsylvania, Philadelphia, PA, USA.

Funding

Drug-drug interactions and kidney disease in hospitalized patientsK08DK124658 · NIDDK · UNIVERSITY OF PENNSYLVANIA · PI MIANO, TODD ANTHONY · 2021 to 2025
$791k
Classical and Alternative Renin-Angiotensin System Dysregulation in Sepsis-Associated AKI: A Reverse Translation ApproachK23DK128562 · NIDDK · UNIVERSITY OF KENTUCKY · PI FLANNERY, ALEXANDER H · 2022 to 2024
$415k
NIDDK NIH HHS K08 DK124658NIDDK NIH HHS K23 DK128562NIH HHS K23DK128562
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Clinical Trials as TopicCritical CareEndpoint DeterminationResearch DesignHumansclinical trialscritical careendpointsoutcomesresearch

Identifiers

PMID38742701
PMCPMC11383190

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.