Evidence map›Paper›PMID 38742509›Full record

ArticleJournal of the American Heart Association2024

Computed Tomography Angiography Characteristics of Thin-Cap Fibroatheroma in Patients With Diabetes.

Keishi Suzuki, Daisuke Kinoshita, Takayuki Niida, Haruhito Yuki, Daichi Fujimoto, Damini Dey, Hang Lee, Iris McNulty, Masamichi Takano, Kyoichi Mizuno and 3 more

Registry-linked trialAbstract read
In one paragraph

Article in Journal of the American Heart Association, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04523194 (Massachusetts General Hospital and Tsuchiura Kyodo General Hospital Coronary Imaging Collaboration), which is not on this map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04523194 active not recruitingnot on this map

Massachusetts General Hospital and Tsuchiura Kyodo General Hospital Coronary Imaging Collaboration

TypeobservationalSponsorMassachusetts General HospitalRan2020 to 2027Enrolled1,000ConditionsAtherosclerosisArmsOptical Coherence Tomography (OCT) and Computed Tomography Angiography (CTA)
3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Keishi SuzukiCardiology Division, Massachusetts General Hospital Harvard Medical School Boston MA USA.ORCID 0009-0001-5543-2420
Daisuke KinoshitaCardiology Division, Massachusetts General Hospital Harvard Medical School Boston MA USA.ORCID 0000-0001-5571-5079
Takayuki NiidaCardiology Division, Massachusetts General Hospital Harvard Medical School Boston MA USA.ORCID 0000-0003-1586-4971
Haruhito YukiCardiology Division, Massachusetts General Hospital Harvard Medical School Boston MA USA.ORCID 0000-0002-2284-7611
Daichi FujimotoCardiology Division, Massachusetts General Hospital Harvard Medical School Boston MA USA.ORCID 0000-0001-5455-674X
Damini DeyBiomedical Imaging Research Institute Cedars-Sinai Medical Center Los Angeles CA USA.ORCID 0000-0003-2236-6970
Hang LeeBiostatistics Center, Massachusetts General Hospital Harvard Medical School Boston MA USA.ORCID 0000-0002-3498-236X
Iris McNultyCardiology Division, Massachusetts General Hospital Harvard Medical School Boston MA USA.ORCID 0009-0009-3962-8034
Masamichi TakanoCardiovascular Center Nippon Medical School Chiba Hokusoh Hospital Inzai Chiba Japan.
Kyoichi MizunoMitsukoshi Health and Welfare Foundation Tokyo Japan.ORCID 0009-0003-9933-9513
Maros FerencikKnight Cardiovascular Institute Oregon Health and Science University Portland OR USA.ORCID 0000-0001-5872-2223
Tsunekazu KakutaDepartment of Cardiology Tsuchiura Kyodo General Hospital Tsuchiura Ibaraki Japan.ORCID 0000-0002-4004-5292
Ik-Kyung JangCardiology Division, Massachusetts General Hospital Harvard Medical School Boston MA USA.ORCID 0000-0002-5796-3006

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIt was recently reported that thin-cap fibroatheroma (TCFA) detected by optical coherence tomography was an independent predictor of future cardiac events in patients with diabetes. However, the clinical usefulness of this finding is limited by the invasive nature of optical coherence tomography. Computed tomography angiography (CTA) characteristics of TCFA have not been systematically studied. The aim of this study was to investigate CTA characteristics of TCFA in patients with diabetes. METHODS AND

resultsPatients with diabetes who underwent preintervention CTA and optical coherence tomography were included. Qualitative and quantitative analyses were performed for plaques on CTA. TCFA was assessed by optical coherence tomography. Among 366 plaques in 145 patients with diabetes, 111 plaques had TCFA. The prevalence of positive remodeling (74.8% versus 50.6%,

conclusionsThe combined qualitative and quantitative plaque analysis of CTA may be helpful in identifying TCFA in patients with diabetes. REGISTRATION INFORMATION: URL: https://www.clinicaltrials.gov; Unique identifier: NCT04523194.

Indexed as

Computed Tomography AngiographyCoronary AngiographyCoronary Artery DiseasePlaque, AtheroscleroticTomography, Optical CoherenceAgedCoronary VesselsDiabetes MellitusFemaleFibrosisHumansMaleMiddle AgedPredictive Value of TestsRetrospective StudiesVascular Calcificationdiabeteshigh‐risk plaqueplaque volumethin‐cap fibroatheroma

Identifiers

PMID38742509
PMCPMC11179821

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.