Evidence map›Paper›PMID 38742199›Full record

ArticleFrontiers in endocrinology2024

Predictive value of bone turnover markers and thyroid indicators for bone metabolism in GD patients after treatment.

Mengxue Su, Jinyan Chai, Wei Zheng, Qiang Jia, Jian Tan, Yajing He, Ruiguo Zhang, Jianlong Men, Wei Liu, Tao Shi and 4 more

Abstract read
In one paragraph

Article in Frontiers in endocrinology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

14 authors.

Mengxue Su *Department of Nuclear Medicine, Tianjin Medical University General Hospital, Tianjin, China.
Jinyan Chai *Department of Nuclear Medicine, Tianjin Medical University General Hospital, Tianjin, China.
Wei ZhengDepartment of Nuclear Medicine, Tianjin Medical University General Hospital, Tianjin, China.
Qiang JiaDepartment of Nuclear Medicine, Tianjin Medical University General Hospital, Tianjin, China.
Jian TanDepartment of Nuclear Medicine, Tianjin Medical University General Hospital, Tianjin, China.
Yajing HeDepartment of Nuclear Medicine, Tianjin Medical University General Hospital, Tianjin, China.
Ruiguo ZhangDepartment of Nuclear Medicine, Tianjin Medical University General Hospital, Tianjin, China.
Jianlong MenPrecision Medicine Center, Tianjin Medical University General Hospital, Tianjin, China.
Wei LiuPrecision Medicine Center, Tianjin Medical University General Hospital, Tianjin, China.
Tao ShiPrecision Medicine Center, Tianjin Medical University General Hospital, Tianjin, China.
Jing RenPrecision Medicine Center, Tianjin Medical University General Hospital, Tianjin, China.
Liyan DongDepartment of General Surgery, Tianjin Medical University General Hospital, Tianjin, China.
Luyi LiuGeorge's School, Middletown, RI, United States.
Zhaowei MengDepartment of Nuclear Medicine, Tianjin Medical University General Hospital, Tianjin, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: To investigate the relationship between bone turnover markers (BTMs) and thyroid indicators in Graves' disease (GD) and to further assess predictive value of changes in early stage retrospectively. Methods: We studied 435 patients with GD and 113 healthy physical examiners retrospectively and followed up these two groups of patients after 6 months. We investigated the correlations between BTMs and other 15 observed factors, and analyzed the predictive value of FT Results: The levels of thyroid hormones and BTMs in GD group were significantly higher than those in control group (P < 0.05) and decreased after 6 months of treatment. FT3, W, Ca and ALP were independent factors in predicting the elevation of OST. Duration of disease, FT3, TSH and ALP were independent factors in predicting the elevation of P1NP. Age, duration of disease, TRAb and ALP were independent factors in predicting the elevation of CTX-1. The AUC of FT Conclusion: BTMs were abnormally elevated in GD and were significantly correlated with serum levels of FT3, FT4, TRAb, Ca, and ALP. FT

Indexed as

BiomarkersBone RemodelingGraves DiseasePredictive Value of TestsAdultAntithyroid AgentsBone and BonesCase-Control StudiesFemaleFollow-Up StudiesHumansMaleMiddle AgedPrognosisRetrospective StudiesThyroid GlandAntithyroid AgentsBiomarkersThyroid HormonesThyroxineTriiodothyroninebone turnover markers (BTMs)CTX (C-terminal telopeptide of type 1 collagen)hyperthyroidosteocalcinP1NPprocollagen type 1 N-terminal propeptide

Identifiers

PMID38742199
PMCPMC11089166

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.