Evidence map›Paper›PMID 38742136›Full record

ArticleEmergency medicine international2024

Does Point-of-Care Ultrasound Affect Fluid Resuscitation Volume in Patients with Septic Shock: A Retrospective Review.

Enyo A Ablordeppey, Amy Zhao, Jeffery Ruggeri, Ahmad Hassan, Laura Wallace, Mansi Agarwal, Sean P Stickles, Christopher Holthaus, Daniel Theodoro

Abstract read
In one paragraph

Article in Emergency medicine international, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Trial
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Enyo A AblordeppeyDepartment of Anaesthesiology, Washington University School of Medicine, St. Louis, MO, USA.ORCID https://orcid.org/0000-0003-4351-6720
Amy ZhaoWashington University School of Medicine, St. Louis, MO, USA.
Jeffery RuggeriDepartment of Emergency Medicine, Washington University School of Medicine, St. Louis, MO, USA.
Ahmad HassanWashington University School of Medicine, St. Louis, MO, USA.
Laura WallaceDepartment of Emergency Medicine, Washington University School of Medicine, St. Louis, MO, USA.
Mansi AgarwalDivision of Biostatistics, Washington University School of Medicine, St. Louis, MO, USA.
Sean P SticklesDepartment of Emergency Medicine, Washington University School of Medicine, St. Louis, MO, USA.
Christopher HolthausDepartment of Emergency Medicine, Washington University School of Medicine, St. Louis, MO, USA.
Daniel TheodoroDepartment of Emergency Medicine, Washington University School of Medicine, St. Louis, MO, USA.ORCID https://orcid.org/0000-0001-6851-4962

Funding

WU INSTITUTE OF CLINICAL AND TRANSLATIONAL SCIENCESUL1TR002345 · NCATS · WASHINGTON UNIVERSITY · PI William G. Powderly · 2017 to 2026
$97.8M
Washington University K12 Program in T4 Implementation ResearchK12HL137942 · NHLBI · WASHINGTON UNIVERSITY · PI DAVILA-ROMAN, VICTOR G. · 2017 to 2021
$3.1M
NCATS NIH HHS UL1 TR002345NHLBI NIH HHS K12 HL137942
6 · The paper itself

Abstract

Background: Fixed, large volume resuscitation with intravenous fluids (IVFs) in septic shock can cause inadvertent hypervolemia, increased medical interventions, and death when unguided by point-of-care ultrasound (POCUS). The primary study objective was to evaluate whether total IVF volume differs for emergency department (ED) septic shock patients receiving POCUS versus no POCUS. Methods: We conducted a retrospective observational cohort study from 7/1/2018 to 8/31/2021 of atraumatic adult ED patients with septic shock. We agreed upon Results: 304 patients met criteria and 26% (78/304) underwent POCUS. Cardiac POCUS demonstrated reduced ejection fraction in 15.4% of patients. Lung ultrasound showed normal findings in 53% of patients. The POCUS vs. non-POCUS cohorts had statistically significant differences for the following variables: higher median lactate (6.7 [IQR 5.2-8.7] vs. 5.6], Conclusions: Among ED patients with septic shock, POCUS was more likely to be used in sicker patients. Patients who had POCUS were given similar volume of crystalloids although these patients were more critically ill. There were no differences in new oxygen requirement or mortality in the POCUS group compared to the non-POCUS group.

Identifiers

PMID38742136
PMCPMC11090677

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.