Evidence map›Paper›PMID 38742044›Full record

ArticleFrontiers in neurology2024

Neurological manifestations of nontuberculous mycobacteria in adults: case series and review of the literature.

Yair Mina, Ahnika Kline, Maura Manion, Dima A Hammoud, Tianxia Wu, Julie Hogan, Irini Sereti, Bryan R Smith, Christa S Zerbe, Steven M Holland and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in neurology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Yair MinaNational Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, United States.
Ahnika KlineNational Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, United States.
Maura ManionNational Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, United States.
Dima A HammoudCenter for Infectious Disease Imaging, Radiology and Imaging Sciences, Clinical Center, National Institutes of Health, Bethesda, MD, United States.
Tianxia WuNational Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, United States.
Julie HoganNational Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, United States.
Irini SeretiNational Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, United States.
Bryan R SmithNational Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, United States.
Christa S ZerbeNational Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, United States.
Steven M HollandNational Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, United States.
Avindra NathNational Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, United States.

Funding

Immunopathogenic Mechanisms of Human Immunodeficiency Virus (HIV) DiseaseZIAAI001121 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI SERETI, IRINI · 2010 to 2025
$27.2M
6 · The paper itself

Abstract

Introduction: Nontuberculous mycobacteria (NTM) mediated infections are important to consider in cases with neuroinflammatory presentations. We aimed to characterize cases of NTM with neurological manifestations at the National Institutes of Health (NIH) Clinical Center and review the relevant literature. Materials and methods: Between January 1995 and December 2020, six cases were identified. Records were reviewed for demographic, clinical, and radiological characteristics. A MEDLINE search found previously reported cases. Data were extracted, followed by statistical analysis to compare two groups [cases with slow-growing mycobacteria (SGM) vs. those with rapidly growing mycobacteria (RGM)] and evaluate for predictors of survival. NIH cases were evaluated for clinical and radiological characteristics. Cases from the literature were reviewed to determine the differences between SGM and RGM cases and to identify predictors of survival. Results: Six cases from NIH were identified (age 41 ± 13, 83% male). Five cases were caused by SGM [ Discussion: NTM infections cause diverse neurological manifestations, with some distinctions between SGM and RGM infections. Tissue sampling may be necessary to establish the diagnosis, and an effort should be made to identify an underlying immune disorder.

Indexed as

infectionsmagnetic resonance imagingneuroimagingneuroinfectious diseasesnontuberculous mycobacteria

Identifiers

PMID38742044
PMCPMC11089811

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.