Evidence map›Paper›PMID 38741637›Full record

ArticleIndian journal of surgical oncology2024

Spontaneous Tumor Lysis Syndrome in a Case of Hepatocellular Carcinoma with Sarcomatoid Differentiation.

Raja Chhabra, Aditya Vidushi, Sajjan Rajpurohit, Jasbir Singh, Md Ali Osama

Abstract readCase Reports
In one paragraph

Article in Indian journal of surgical oncology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Raja ChhabraDepartment of Medical Oncology, BLK-MAX Super Speciality Hospital, Pusa Road, New Delhi, India.ORCID 0000-0003-3363-6526
Aditya VidushiDepartment of Medical Oncology, BLK-MAX Super Speciality Hospital, Pusa Road, New Delhi, India.
Sajjan RajpurohitDepartment of Medical Oncology, BLK-MAX Super Speciality Hospital, Pusa Road, New Delhi, India.
Jasbir SinghDepartment of Pathology, BLK-MAX Super Speciality Hospital, Pusa Road, New Delhi, India.
Md Ali OsamaDepartment of Pathology, Lady Hardinge Medical College, New Delhi, India.ORCID 0000-0002-0660-9939

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sarcomatoid hepatocellular carcinoma is a rare histologic variant of primary liver cancer comprising of malignant spindle cells and typical hepatocellular carcinoma (HCC). In terms of clinical presentation, they usually exhibit extensive tumor burden due to their larger size and a metastatic disease at the time of diagnosis as compared to conventional HCC. Tumor lysis syndrome is an oncological emergency, usually seen after cytotoxic chemotherapy in haematological malignancies. Here, we highlight a case of 76-year old male with no comorbidities, presenting with an excruciating backache and a paravertebral soft tissue mass and multiple osteolytic lesions, was clinically suspected to be a plasma cell neoplasm. On further evaluation, the patient was diagnosed of a sarcomatoid variant of hepatocellular carcinoma. This report showcases multiple rare findings by the presence of non-specific symptoms, non-cirrhotic liver, normal serum alpha protein levels and the occurrence of a spontaneous tumor lysis syndrome in a solid malignancy.

Indexed as

ArginaseCarcinomaHepatocellularLysisSarcomaSpindleSpontaneousTumor

Identifiers

PMID38741637
PMCPMC11088581

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.