Evidence map›Paper›PMID 38741445›Full record

Observational studyAnaesthesiology intensive therapy2024

Predictors of outcomes of patients ≥ 80 years old admitted to intensive care units in Poland - a post-hoc analysis of the VIP2 prospective observational study.

Paweł Melchior Pasieka, Michał Kurek, Wojciech Skupnik, Evan Skwara, Valentyn Bezshapkin, Jakub Fronczek, Anna Kluzik, Bartosz Kudliński, Szymon Białka, Dorota Studzińska and 37 more

Abstract readObservational StudyMulticenter Study
In one paragraph

Observational study in Anaesthesiology intensive therapy, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

47 authors.

Paweł Melchior PasiekaCentre for Intensive Care and Perioperative Medicine, Jagiellonian University Medical College, Krakow, Poland.
Michał KurekCentre for Intensive Care and Perioperative Medicine, Jagiellonian University Medical College, Krakow, Poland.
Wojciech SkupnikCentre for Intensive Care and Perioperative Medicine, Jagiellonian University Medical College, Krakow, Poland.
Evan SkwaraCentre for Intensive Care and Perioperative Medicine, Jagiellonian University Medical College, Krakow, Poland.
Valentyn BezshapkinCentre for Intensive Care and Perioperative Medicine, Jagiellonian University Medical College, Krakow, Poland.
Jakub FronczekCentre for Intensive Care and Perioperative Medicine, Jagiellonian University Medical College, Krakow, Poland.
Anna KluzikDepartment of Anaesthesiology, Intensive Therapy and Pain Treatment, Poznan University of Medical Sciences, Poznan, Poland.
Bartosz KudlińskiClinical Department of Anaesthesiology and Intensive Care, University Hospital in Zielona Gora, Poland.
Szymon BiałkaDepartment of Anaesthesiology and Critical Care, School of Medicine with Division of Dentistry in Zabrze, Medical University of Silesia, Zabrze, Poland.
Dorota StudzińskaCentre for Intensive Care and Perioperative Medicine, Jagiellonian University Medical College, Krakow, Poland.
Łukasz KrzychDepartment of Anaesthesiology and Intensive Care, University Clinical Centre, School of Medicine in Katowice - Medical University of Silesia, Katowice, Poland.
Szymon CzajkaDepartment of Anaesthesiology and Intensive Care, University Clinical Centre, School of Medicine in Katowice - Medical University of Silesia, Katowice, Poland.
Jan StefaniakDepartment of Anaesthesiology and Intensive Therapy, Faculty of Medicine, Medical University of Gdansk, Poland.
Radosław OwczukDepartment of Anaesthesiology and Intensive Therapy, Faculty of Medicine, Medical University of Gdansk, Poland.
Joanna Sołek-PastuszkaDepartment of Clinical Anaesthesiology and Intensive Therapy, Pomeranian Medical University SPSK 1, Szczecin, Poland.
Jowita BiernawskaDepartment of Clinical Anaesthesiology and Intensive Therapy, Pomeranian Medical University SPSK 1, Szczecin, Poland.
Joanna ZorskaDepartment of Anaesthesiology and Intensive Care Medicine, Jagiellonian University Medical College, Krakow, Poland.
Paweł KrawczykDepartment of Anaesthesiology and Intensive Care Medicine, Jagiellonian University Medical College, Krakow, Poland.
Katarzyna CwylAnesthesia and Intensive Care Unit, Regional Health Centre in Lublin, Poland.
Maciej ŻukowskiDepartment of Anaesthesiology, Intensive Therapy and Acute Intoxications, Pomeranian Medical University in Szczecin, Poland.
Katarzyna KotfisDepartment of Anaesthesiology, Intensive Therapy and Acute Intoxications, Pomeranian Medical University in Szczecin, Poland.
Małgorzata Zegan-BarańskaDepartment of Anaesthesiology, Intensive Therapy and Acute Intoxications, Pomeranian Medical University in Szczecin, Poland.
Agnieszka WieczorekAnaesthesia and Intensive Care Unit, 4th Military Hospital in Wroclaw, Poland.
Wojciech MudynaDepartment of Anaesthesiology and Intensive Therapy, Ludwik Rydygier Memorial Specialist Hospital in Krakow, Poland.
Mariusz PiechotaDepartment of Anaesthesiology and Intensive Therapy - Centre for Artificial Extracorporeal Kidney and Liver Support, Lodz, Poland.
Szymon BernasDepartment of Anaesthesiology and Intensive Therapy - Centre for Artificial Extracorporeal Kidney and Liver Support, Lodz, Poland.
Waldemar MachałaDepartment of Anaesthesiology and Intensive Therapy, Central Teaching Hospital of the Medical University of Lodz, Poland.
Łukasz SadowskiDepartment of Anaesthesiology and Intensive Therapy, Central Teaching Hospital of the Medical University of Lodz, Poland.
Marta SerwaDepartment of Anaesthesiology and Intensive Therapy, Central Teaching Hospital of the Medical University of Lodz, Poland.
Mirosław Czuczwar2nd Department of Anaesthesiology and Intensive Care, Medical University of Lublin, Poland.
Michał Borys2nd Department of Anaesthesiology and Intensive Care, Medical University of Lublin, Poland.
Mirosław ZiętkiewiczDepartment of Anaesthesiology and Intensive Care Medicine, Jagiellonian University Medical College, Krakow, Poland.
Natalia KozeraDepartment of Anaesthesiology and Intensive Therapy, Wroclaw University Hospital, Wroclaw Medical University, Wroclaw, Poland.
Barbara AdamikClinical Department of Anaesthesiology and Intensive Therapy, Wroclaw Medical University, Wroclaw, Poland.
Waldemar GoździkClinical Department of Anaesthesiology and Intensive Therapy, Wroclaw Medical University, Wroclaw, Poland.
Paweł NasiłowskiDepartment of Anaesthesiology and Intensive Therapy, G. Narutowicz Specialist Hospital in Krakow, Poland.
Paweł ZatorskiI Department of Anaesthesiology and Intensive Care, University Clinical Center of the Medical University of Warsaw - Infant Jesus Clinical Hospital, Warsaw, Poland.
Janusz TrzebickiI Department of Anaesthesiology and Intensive Care, University Clinical Center of the Medical University of Warsaw - Infant Jesus Clinical Hospital, Warsaw, Poland.
Piotr GałkinDepartment of Anaesthesiology and Intensive Care, Regional Hospital in Bialystok, Poland.
Ryszard GawdaDepartment of Anaesthesiology and Intensive Care, Institute of Medical Sciences, University of Opole, Poland.
Urszula KościuczukDepartment of Anaesthesiology and Intensive Care, Medical University of Bialystok, Poland.
Waldemar CyrankiewiczDepartment of Anaesthesiology and Intensive Therapy, Antoni Jurasz University Hospital No. 1, Bydgoszcz, Poland.
Katarzyna SierakowskaDepartment of Anaesthesiology and Intensive Therapy, Antoni Jurasz University Hospital No. 1, Bydgoszcz, Poland.
Wojciech GolaFaculty of Medicine and Health Sciences, Jan Kochanowski University, Kielce, Poland.
Hubert Hymczak1st Department of Anaesthesiology and Intensive Care, John Paul II Hospital in Krakow, Poland.
Hans FlaattenDepartment of Anaesthesia and Intensive Care, Haukeland University Hospital, Bergen, Norway.
Wojciech SzczeklikCentre for Intensive Care and Perioperative Medicine, Jagiellonian University Medical College, Krakow, Poland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionElderly patients pose a significant challenge to intensive care unit (ICU) clinicians. In this study we attempted to characterise the population of patients over 80 years old admitted to ICUs in Poland and identify associations between clinical features and short-term outcomes. MATERIAL AND

methodsThe study is a post-hoc analysis of the Polish cohort of the VIP2 European prospective observational study enrolling patients > 80 years old admitted to ICUs over a 6-month period. Data including clinical features, clinical frailty scale (CFS), geriatric scales, interventions within the ICU, and outcomes (30-day and ICU mortality and length of stay) were gathered. Univariate analyses comparing frail (CFS > 4) to non-frail patients and survivors to non-survivors were performed. Multivariable models with CFS, activities of daily living score (ADL), and the cognitive decline questionnaire IQCODE as predictors and ICU or 30-day mortality as outcomes were formed.

resultsA total of 371 patients from 27 ICUs were enrolled. Frail patients had significantly higher ICU (58% vs. 44.45%, P = 0.03) and 30-day (65.61% vs. 54.14%, P = 0.01) mortality compared to non-frail counterparts. The survivors had significantly lower SOFA score, CFS, ADL, and IQCODE than non-survivors. In multivariable analysis CFS (OR 1.15, 95% CI: 1.00-1.34) and SOFA score (OR 1.29, 95% CI: 1.19-1.41) were identified as significant predictors for ICU mortality; however, CFS was not a predictor for 30-day mortality ( P = 0.07). No statistical significance was found for ADL, IQCODE, polypharmacy, or comorbidities.

conclusionsWe found a positive correlation between CFS and ICU mortality, which might point to the value of assessing the score for every patient admitted to the ICU. The older Polish ICU patients were characterised by higher mortality compared to the other European countries.

Indexed as

Intensive Care UnitsActivities of Daily LivingAged, 80 and overCohort StudiesFemaleFrail ElderlyFrailtyGeriatric AssessmentHospital MortalityHumansLength of StayMalePolandProspective Studiesfrailtygeriatric populationintensive caremortality analysismulticentre studyobservational studyprospective studysepsisVIP study

Identifiers

PMID38741445
PMCPMC11022638

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.