Evidence map›Paper›PMID 38741175›Full record

ReviewMilitary Medical Research2024

Biomaterials science and surface engineering strategies for dental peri-implantitis management.

Ya-Meng Yu, Yu-Pu Lu, Ting Zhang, Yu-Feng Zheng, Yun-Song Liu, Dan-Dan Xia

Abstract readReview
In one paragraph

Review in Military Medical Research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

46 citing papers in PubMed.

  1. ROS-responsive HBioactive materials · 2027
    Article
  2. Article
  3. Article
  4. Review
  5. Osseointegrated implant labial displacement with no mobility in maxillary anterior region: A clinical report.Journal of prosthodontics : official journal of the American College of Prosthodontists · 2026
    Article
  6. [Frontier research on smart delivery biomaterials in the field of oral tissue engineering].Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology · 2026
    Review
  7. Review
  8. Review
  9. Review
  10. Bacteriophage-mediated reduction of Pseudomonas aeruginosa biofilm on titanium surfaces for biomedical applications.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2026
    Article
  11. Review
  12. Review
  13. Review
  14. Article
  15. Review
  16. Review
  17. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ya-Meng YuDepartment of Dental Materials, Peking University School and Hospital of Stomatology, Beijing, 100081, China.
Yu-Pu LuDepartment of Dental Materials, Peking University School and Hospital of Stomatology, Beijing, 100081, China.
Ting ZhangSchool of Materials Science and Engineering, Peking University, Beijing, 100871, China.
Yu-Feng ZhengSchool of Materials Science and Engineering, Peking University, Beijing, 100871, China. yfzheng@pku.edu.cn.
Yun-Song LiuNational Center for Stomatology & National Clinical Research Center for Oral Diseases & National Engineering Research Center of Oral Biomaterials and Digital Medical Devices, Beijing Key Laboratory of Digital Stomatology & NHC Key Laboratory of Digital Stomatology & NMPA Key Laboratory for Dental Materials, Beijing, 100081, China. liuyunsong@hsc.pku.edu.cn.
Dan-Dan XiaDepartment of Dental Materials, Peking University School and Hospital of Stomatology, Beijing, 100081, China. dandanxia@pku.edu.cn.

Funding

Beijing Natural Science Foundation L212014Beijing Nova Program 20230484459National Clinical Key Discipline Construction Project PKUSSNKP-T202103National Key Research and Development Program of China 2023YFC2412600National Natural Science Foundation of China 52171233National Natural Science Foundation of China 52271243National Natural Science Foundation of China 82170929National Natural Science Foundation of China 82370924
6 · The paper itself

Abstract

Peri-implantitis is a bacterial infection that causes soft tissue inflammatory lesions and alveolar bone resorption, ultimately resulting in implant failure. Dental implants for clinical use barely have antibacterial properties, and bacterial colonization and biofilm formation on the dental implants are major causes of peri-implantitis. Treatment strategies such as mechanical debridement and antibiotic therapy have been used to remove dental plaque. However, it is particularly important to prevent the occurrence of peri-implantitis rather than treatment. Therefore, the current research spot has focused on improving the antibacterial properties of dental implants, such as the construction of specific micro-nano surface texture, the introduction of diverse functional coatings, or the application of materials with intrinsic antibacterial properties. The aforementioned antibacterial surfaces can be incorporated with bioactive molecules, metallic nanoparticles, or other functional components to further enhance the osteogenic properties and accelerate the healing process. In this review, we summarize the recent developments in biomaterial science and the modification strategies applied to dental implants to inhibit biofilm formation and facilitate bone-implant integration. Furthermore, we summarized the obstacles existing in the process of laboratory research to reach the clinic products, and propose corresponding directions for future developments and research perspectives, so that to provide insights into the rational design and construction of dental implants with the aim to balance antibacterial efficacy, biological safety, and osteogenic property.

Indexed as

Biocompatible MaterialsDental ImplantsPeri-ImplantitisAnti-Bacterial AgentsBiofilmsHumansSurface PropertiesAnti-Bacterial AgentsBiocompatible MaterialsDental ImplantsAnaerobic bacteriaAntibacterial activityDental implantOsteogenic propertyPeri-implantitis

Identifiers

PMID38741175
PMCPMC11089802

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.