Evidence map›Paper›PMID 38740719›Full record

ArticleInternational journal of computer assisted radiology and surgery2024

Segmentation of mediastinal lymph nodes in CT with anatomical priors.

Tejas Sudharshan Mathai, Bohan Liu, Ronald M Summers

Abstract read
In one paragraph

Article in International journal of computer assisted radiology and surgery, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Annotation-efficient deep learning detection and measurement of mediastinal lymph nodes in CT.International journal of computer assisted radiology and surgery · 2026
    Article
  5. Review
  6. Subcutaneous edema segmentation on abdominal CT using multi-class labels and iterative annotation.International journal of computer assisted radiology and surgery · 2025
    Article
  7. Weakly supervised detection of pheochromocytomas and paragangliomas in CT using noisy data.Computerized medical imaging and graphics : the official journal of the Computerized Medical Imaging Society · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Tejas Sudharshan MathaiClinical Center, National Institutes of Health (NIH), Bethesda, MD, USA. tejas.mathai@nih.gov.ORCID http://orcid.org/0009-0005-8440-1702
Bohan LiuDepartment of Radiology, School of Medicine and Health Sciences, George Washington University, Washington, DC, USA.
Ronald M SummersClinical Center, National Institutes of Health (NIH), Bethesda, MD, USA.

Funding

Computer Aided Detection for Radiologic ImagesZ01CL040004 · CLC · CLINICAL CENTER · PI SUMMERS, RONALD M. · 2003 to 2008
$41k
Computer Aided Detection for Radiologic ImagesZIACL040004 · CLC · CLINICAL CENTER · PI SUMMERS, RONALD M. · 2009 to 2025
$0k
Intramural NIH HHS Z01 CL040004
6 · The paper itself

Abstract

purposeLymph nodes (LNs) in the chest have a tendency to enlarge due to various pathologies, such as lung cancer or pneumonia. Clinicians routinely measure nodal size to monitor disease progression, confirm metastatic cancer, and assess treatment response. However, variations in their shapes and appearances make it cumbersome to identify LNs, which reside outside of most organs.

methodsWe propose to segment LNs in the mediastinum by leveraging the anatomical priors of 28 different structures (e.g., lung, trachea etc.) generated by the public TotalSegmentator tool. The CT volumes from 89 patients available in the public NIH CT Lymph Node dataset were used to train three 3D off-the-shelf nnUNet models to segment LNs. The public St. Olavs dataset containing 15 patients (out-of-training-distribution) was used to evaluate the segmentation performance.

resultsFor LNs with short axis diameter

conclusionTo our knowledge, we are the first to harness 28 distinct anatomical priors to segment mediastinal LNs, and our work can be extended to other nodal zones in the body. The proposed method has the potential for improved patient outcomes through the identification of enlarged nodes in initial staging CT scans.

Indexed as

Lymph NodesMediastinumTomography, X-Ray ComputedHumansImaging, Three-DimensionalLung NeoplasmsLymphatic MetastasisAnatomical priorsCTDeep learningLymph nodeMediastinumSegmentation

Identifiers

PMID38740719
PMCPMC11329534

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.