Evidence map›Paper›PMID 38740674›Full record

ArticleIrish journal of medical science2024

The potential protective role of vitamin D and calcium supplements in reducing cardiovascular disease risk among elderly patients with osteopenia.

Ramada R Khasawneh, Hana S Al-Soudi, Ejlal Abu-El-Rub, Ayman Alzu'bi, Raed M Al-Zoubi

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Article in Irish journal of medical science, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ramada R KhasawnehDepartment of Basic Medical Sciences, Faculty of Medicine, Yarmouk University, Irbid, 211-63, Jordan.
Hana S Al-SoudiNuclear Medicine, King Hussein Medical Center, Royal Medical Services, Amman, Jordan.ORCID http://orcid.org/0000-0001-9928-4688
Ejlal Abu-El-RubDepartment of Basic Medical Sciences, Faculty of Medicine, Yarmouk University, Irbid, 211-63, Jordan.ORCID http://orcid.org/0000-0001-9217-2560
Ayman Alzu'biDepartment of Basic Medical Sciences, Faculty of Medicine, Yarmouk University, Irbid, 211-63, Jordan.ORCID http://orcid.org/0000-0001-7848-7080
Raed M Al-ZoubiSurgical Research Section, Department of Surgery, Hamad Medical Corporation & Men's Health, Doha, Qatar. ralzoubi@hamad.qa.ORCID http://orcid.org/0000-0002-0548-429X

Funding

Yarmouk University 29/2020
6 · The paper itself

Abstract

backgroundCardiovascular disease and low bone mineral density are major health problems in the elderly. These two conditions are considered independent of each other and age-related diseases. The aim of this study is to investigate the association between low bone mineral density (BMD) and cardiovascular disease (CVD) incidents, and the effect of vitamin D and calcium supplement on the incidence of CVD in patients with low BMD.

methodsA total of 1047 patients (597 females/450 males) with the age of 65 years and more were diagnosed with osteopenia for 13 years or more. The study also included 220 patients (107 females/113 males) with osteopenia who already took calcium and vitamin D continually since their diagnosis. BMD was measured by dual-energy X-ray absorptiometry. The incidence of any cardiovascular diseases in the study patients and the presence of corresponding risk factors were collected and analyzed.

resultsIn both elderly Arab females and males, there was an association between total hip and femoral neck BMD and the possibility to have CVD. On the other hand, the results showed that patients who use calcium and vitamin D supplements showed a significant reduction in the incidence of CVD comparing to the non-treated patients.

conclusionLow total hip and femoral neck BMD were associated with a higher chance to have CVD incidents in both elderly Arab males and females; moreover, calcium and vitamin D supplements have a possible protective role in reducing cardiovascular disease in elderly patients with osteopenia.

Indexed as

Bone DensityBone Diseases, MetabolicCardiovascular DiseasesDietary SupplementsVitamin DAgedAged, 80 and overCalciumFemaleHumansIncidenceMaleRisk FactorsCalciumVitamin DBone mineral densityCalciumCardiovascular diseaseDax scanVitamin D

Identifiers

PMID38740674
PMCPMC11449995

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.