Evidence map›Paper›PMID 38740642›Full record

ArticleJapanese journal of radiology2024

Idiopathic dendriform pulmonary ossification as the phenotype of interstitial lung abnormalities: CT-pathologic correlation and prevalence.

Midori Ueno, Ryoko Egashira, Mikiko Hashisako, Kiminori Fujimoto, Taiki Fukuda, Yoshiko Hayashida, Hiromitsu Sumikawa, Junya Tominaga, Tomonori Tanaka, Yasuhiro Terasaki and 6 more

Abstract read
PubMed Full text at PMC Publisher
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Article in Japanese journal of radiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Pulmonary ossification: a review.Journal of thoracic disease · 2025
    Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Midori UenoDepartment of Radiology, University of Occupational and Environmental Health School of Medicine, 1-1 Iseigaoka, Kitakyushu City, Fukuoka, 807-8555, Japan. mueno@med.uoeh-u.ac.jp.ORCID http://orcid.org/0009-0000-1506-1306
Ryoko EgashiraDepartment of Radiology, Faculty of Medicine, Saga University, 5-1-1, Nabesima, Saga City, Saga, 849-8501, Japan.
Mikiko HashisakoDepartment of Anatomic Pathology, Pathological Sciences, Graduate School of Medicine Sciences, Kyushu University, 3-1-1, Maedashi, Fukuoka City, Fukuoka, 812-8582, Japan.
Kiminori FujimotoDepartment of Radiology, Kurume University School of Medicine, 67, Asahimachi, Kurume City, Fukuoka, 830-0011, Japan.
Taiki FukudaDepartment of Radiology, The Jikei University School of Medicine, 3-25-8, Nishishinbashi, Minato-Ku, Tokyo, 105-8461, Japan.
Yoshiko HayashidaDepartment of Radiology, University of Occupational and Environmental Health School of Medicine, 1-1 Iseigaoka, Kitakyushu City, Fukuoka, 807-8555, Japan.
Hiromitsu SumikawaDepartment of Radiology, National Hospital Organization Kinki-Chuo Chest Medical Center, 1180, Nagasonecyo, Kita-Ku, Sakai City, Osaka, 591-8555, Japan.
Junya TominagaDepartment of Diagnostic Radiology, Tohoku University School of Medicine, 1-1, Seiryoucyo, Aoba-Ku, Sendai City, Miyagi, 980-8574, Japan.
Tomonori TanakaDepartment of Diagnostic Pathology, Kobe University Hospital, 7-5-2, Kusumachi, Cyuoh-Ku, Kobe City, Hyogo, 65017, Japan.
Yasuhiro TerasakiDepartment of Analytic Human Pathology, Nippon Medical School Hospital, 1-1-5, Sendaki, Bunkyo-Ku, Tokyo, 113-8603, Japan.
Junya FukuokaDepartment of Pathology Informatics, Nagasaki University Graduate School of Biomedical Sciences, 1-7-1, Sakamoto, Nagasaki City, Nagasaki, 852-8501, Japan.
Yasuhiko NishiokaDepartment of Respiratory Medicine and Rheumatology, Graduate School of Biomedical Sciences, Tokushima University, 2-50-1, Kuramotocyo, Tokushima City, Tokusima, 770-0042, Japan.
Takatoshi AokiDepartment of Radiology, University of Occupational and Environmental Health School of Medicine, 1-1 Iseigaoka, Kitakyushu City, Fukuoka, 807-8555, Japan.
Toshifumi GabataDepartment of Radiology, Kanazawa University Graduate School of Medical Science, 13-1, Takaramachi, Kanazawa City, Isihikawa, 920-8641, Japan.
Hiroto HatabuDepartment of Radiology, Brigham and Women's Hospital, Harvard Medical School, 75, Francis Street, Boston, 02115, USA.
Takeshi JohkohDepartment of Radiology, Kansai Rosai Hospital, 3-1-69, Inabaso, Amagasaki City, Hyogo, 660-0064, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background and purposeIdiopathic dendriform pulmonary ossification (DPO) is mostly asymptomatic, and detected incidentally in lung CT. There have been no reports on the precise CT-pathologic correlation and the prevalence of idiopathic DPO. This study aimed to clarify the histological background and prevalence of idiopathic DPO. MATERIALS AND

methodsSixteen patients with histologically confirmed idiopathic DPO (12 men and 4 women; mean age, 38.8 years; range 22-56 years) were identified in a nationwide epidemiological survey. Local HRCT findings of pre-biopsy examinations, such as branching, round, linear structures with or without high attenuation were compared side by side with histological findings. The attenuation of branching, round, and linear structures was classified into three-point levels on bone window images (width, 2500 HU; level, 500 HU). Furthermore, we collected continuous pulmonary CT images of 8111 cases for checking up metastasis from extrathoracic malignancy at a single institution, and evaluated the prevalence of interstitial lung abnormalities (ILAs) and DPO.

resultsIn all 16 cases, branching (n = 15, 93%), round (n = 5, 31%), or linear (n = 5, 31%) structures were identified, histologically corresponding to dendriform ossification and cicatricial organizing pneumonia (OP)/fibrosis. Histologically, ossification was confirmed in all the 16 patients. However, in two cases, a highly attenuated structure could not be detected on the pre-biopsy CT of the same area. Regarding the prevalence of idiopathic DPO, 283 (3.5%) of 8111 patients had ILAs, of which a total of 26 (0.3% of all cases, 9.2% of ILAs cases) had DPO.

conclusionIdiopathic DPO showed linear or branching structures with or without high attenuation on CT, corresponded to ossification, cicatricial OP/fibrosis. DPO was seen in 9.2% of ILAs cases. Idiopathic DPO is one of pathologic phenotypes of ILAs.

Indexed as

Lung Diseases, InterstitialOssification, HeterotopicPhenotypeTomography, X-Ray ComputedAdultFemaleHumansLungMaleMiddle AgedPrevalenceYoung AdultCicatricial organizing pneumoniaDendriform pulmonary ossificationInterstitial lung abnormalitiesRadiologic–pathologic correlationThin-section CT

Identifiers

PMID38740642
PMCPMC11364601

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.