Evidence map›Paper›PMID 38740620›Full record

ReviewWorld journal of urology2024

Conservative treatment of Peyronie's disease: a guide.

Marco Cosentino, Michele Di Nauta, Luca Boeri, Giordana Ferraioli, Gianpaolo Lucignani, Anna Ricapito, Franco Gadda, Massimo Iafrate, Mariangela Mancini, Fabrizio Dal Moro and 4 more

Abstract readReview
PubMed Publisher
In one paragraph

Review in World journal of urology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Marco CosentinoUro-Andrology Department, Casa di Cura Villa Maria, Via delle Melette 22, 35138, Padua, Italy. androcosentino@gmail.com.
Michele Di NautaDepartment of Urology and Organ Transplantation, Università di Foggia, Foggia, Italy.
Luca BoeriDepartment of Urology, Foundation IRCCS Ca' Granda Ospedale Maggiore Policlinico, University of Milan, Milan, Italy.
Giordana FerraioliUrology Clinic, Department of Surgical, Oncological and Gastroenterological Sciences, Padova University, Padua, Italy.
Gianpaolo LucignaniDepartment of Urology, Foundation IRCCS Ca' Granda Ospedale Maggiore Policlinico, University of Milan, Milan, Italy.
Anna RicapitoDepartment of Urology and Organ Transplantation, Università di Foggia, Foggia, Italy.
Franco GaddaDepartment of Urology, Foundation IRCCS Ca' Granda Ospedale Maggiore Policlinico, University of Milan, Milan, Italy.
Massimo IafrateUrology Clinic, Department of Surgical, Oncological and Gastroenterological Sciences, Padova University, Padua, Italy.
Mariangela ManciniUrology Clinic, Department of Surgical, Oncological and Gastroenterological Sciences, Padova University, Padua, Italy.
Fabrizio Dal MoroUrology Clinic, Department of Surgical, Oncological and Gastroenterological Sciences, Padova University, Padua, Italy.
Eduard Ruiz-CastañeAndrology Department, Fundacio Puigvert, Universitat Autonoma de Barcelona, Barcelona, Spain.
Carlo BettocchiDepartment of Urology and Organ Transplantation, Università di Foggia, Foggia, Italy.
Emanuele MontanariDepartment of Urology, Foundation IRCCS Ca' Granda Ospedale Maggiore Policlinico, University of Milan, Milan, Italy.
Nikolaos SofikitisDepartment of Urology, Ioannina University School of Medicine, Ioannina, Greece.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo review the literature on the topic, to suggest a common line of treatment applicable across a wide community of specialists, and to contribute in maintaining the high level of interest in this disease.

methodsA comprehensive and exhaustive review of the literature was performed, identifying hundreds of articles on the topic.

resultsPeyronie's disease is a condition that has been recognized, studied, and treated for centuries; despite this, if one excludes surgery in cases in which the deformity is stable, no clear treatment (or line of treatment) is available for complete relief of signs and symptoms. Treatment options were divided into local, oral, and injection therapy, and a wide variety of drugs, remedies, and options were identified.

conclusionsLow-intensity extracorporeal shock wave therapy, vacuum therapy, penile traction therapy, phosphodiesterase type 5 inhibitors, hyaluronic acid, and collagenase of Clostridium histolyticum may be recommended only in specific contexts. Further studies on individual options or potential combinations are required.

Indexed as

Conservative TreatmentPenile IndurationExtracorporeal Shockwave TherapyHumansHyaluronic AcidMaleMicrobial CollagenasePhosphodiesterase 5 InhibitorsPractice Guidelines as TopicTractionHyaluronic AcidMicrobial CollagenasePhosphodiesterase 5 InhibitorsAcute phaseConservative treatmentCurvatureMedical treatmentPeyronie’s disease

Identifiers

PMID38740620

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.