Evidence map›Paper›PMID 38740393›Full record

ArticleNeurosciences (Riyadh, Saudi Arabia)2024

Atypical meningiomas compared to other WHO Grade 2 meningiomas: Histological features and prognosis.

Abdulrazag Ajlan, Saif Almeshari, Sarah Basindwah, Majed Aljohani, Yazed Alharbi, Fahad Aldhowaihy, Hisham Alkhaldi, Ashwag Alqurashi

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Neurosciences (Riyadh, Saudi Arabia), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Abdulrazag AjlanFrom the Division of Neurosurgery (Ajlan, Basindwah, Alqurashi), Department of Surgery, College of Medicine, King Saud University, from the College of Medicine (Almeshari, Aljohani, Alharbi, Aldhowaihy), King Saud University, and from the Department of Pathology (Alkhaldi), College of Medicine, King Saud University, Riyadh, Kingdom of Saudi Arabia.
Saif AlmeshariFrom the Division of Neurosurgery (Ajlan, Basindwah, Alqurashi), Department of Surgery, College of Medicine, King Saud University, from the College of Medicine (Almeshari, Aljohani, Alharbi, Aldhowaihy), King Saud University, and from the Department of Pathology (Alkhaldi), College of Medicine, King Saud University, Riyadh, Kingdom of Saudi Arabia.ORCID https://orcid.org/0000-0002-7403-038X
Sarah BasindwahFrom the Division of Neurosurgery (Ajlan, Basindwah, Alqurashi), Department of Surgery, College of Medicine, King Saud University, from the College of Medicine (Almeshari, Aljohani, Alharbi, Aldhowaihy), King Saud University, and from the Department of Pathology (Alkhaldi), College of Medicine, King Saud University, Riyadh, Kingdom of Saudi Arabia.
Majed AljohaniFrom the Division of Neurosurgery (Ajlan, Basindwah, Alqurashi), Department of Surgery, College of Medicine, King Saud University, from the College of Medicine (Almeshari, Aljohani, Alharbi, Aldhowaihy), King Saud University, and from the Department of Pathology (Alkhaldi), College of Medicine, King Saud University, Riyadh, Kingdom of Saudi Arabia.
Yazed AlharbiFrom the Division of Neurosurgery (Ajlan, Basindwah, Alqurashi), Department of Surgery, College of Medicine, King Saud University, from the College of Medicine (Almeshari, Aljohani, Alharbi, Aldhowaihy), King Saud University, and from the Department of Pathology (Alkhaldi), College of Medicine, King Saud University, Riyadh, Kingdom of Saudi Arabia.
Fahad AldhowaihyFrom the Division of Neurosurgery (Ajlan, Basindwah, Alqurashi), Department of Surgery, College of Medicine, King Saud University, from the College of Medicine (Almeshari, Aljohani, Alharbi, Aldhowaihy), King Saud University, and from the Department of Pathology (Alkhaldi), College of Medicine, King Saud University, Riyadh, Kingdom of Saudi Arabia.
Hisham AlkhaldiFrom the Division of Neurosurgery (Ajlan, Basindwah, Alqurashi), Department of Surgery, College of Medicine, King Saud University, from the College of Medicine (Almeshari, Aljohani, Alharbi, Aldhowaihy), King Saud University, and from the Department of Pathology (Alkhaldi), College of Medicine, King Saud University, Riyadh, Kingdom of Saudi Arabia.
Ashwag AlqurashiFrom the Division of Neurosurgery (Ajlan, Basindwah, Alqurashi), Department of Surgery, College of Medicine, King Saud University, from the College of Medicine (Almeshari, Aljohani, Alharbi, Aldhowaihy), King Saud University, and from the Department of Pathology (Alkhaldi), College of Medicine, King Saud University, Riyadh, Kingdom of Saudi Arabia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo study each atypical feature in atypical meningioma versus other grade 2 meningiomas and its possible relation to recurrence.

methodsThis is a retrospective study of patients with WHO grade 2 meningioma operated in our institution between 01/2008 and 12/2020. The rate of recurrence, reoperation and readmission were recorded during the follow-up period. A statistical analysis was done to determine the significance of each pathological feature in regard to recurrence.

resultsA total of 74 patients were included as WHO grade 2 meningioma with 60 (81%) patients having an AM and 14 (19%) patients with chordoid or clear cell meningioma. The mean age was 51 years±14. The most common location was meningioma abutting the frontal lobe (convexity). Major atypical features were more noted in the AM, however, there was no significant difference between AM and other types of meningioma. Increased Nuclear cytoplasmic ratio and cellularity were found significantly more in AM. The recurrence rate was 16.2%. No specific pathology feature (major or minor) nor the type of Grade 2 meningioma was significantly related to recurrence.

conclusionThe types of WHO grade 2 meningiomas have similar prognosis and recurrence rates. There is no significant difference between the atypical features in indicating a more aggressive nature or risk of recurrence in grade 2 meningiomas.

Indexed as

Meningeal NeoplasmsMeningiomaNeoplasm Recurrence, LocalAdultAgedFemaleHumansMaleMiddle AgedNeoplasm GradingPrognosisRetrospective Studies

Identifiers

PMID38740393
PMCPMC11305365

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.