Evidence map›Paper›PMID 38739798›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2024

Targeting the

Harry R King, Mark Bycroft, Thanh-Binh Nguyen, Geoff Kelly, Alexander A Vinogradov, Pamela J E Rowling, Katherine Stott, David B Ascher, Hiroaki Suga, Laura S Itzhaki and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Harry R KingDepartment of Pathology, University of Cambridge, Cambridge CB2 1QP, United Kingdom.
Mark BycroftDepartment of Pharmacology, University of Cambridge, Cambridge CB2 1PD, United Kingdom.
Thanh-Binh NguyenSchool of Chemistry and Molecular Biosciences, University of Queensland, Brisbane QLD 4067, Australia.
Geoff KellyNMR Centre, Francis Crick Institute, London NW1 1AT, United Kingdom.
Alexander A VinogradovDepartment of Chemistry, Graduate School of Science, University of Tokyo, Tokyo 113-0033, Japan.
Pamela J E RowlingDepartment of Pharmacology, University of Cambridge, Cambridge CB2 1PD, United Kingdom.
Katherine StottDepartment of Biochemistry, University of Cambridge, Cambridge CB2 1GA, United Kingdom.ORCID 0000-0002-4014-1188
David B AscherSchool of Chemistry and Molecular Biosciences, University of Queensland, Brisbane QLD 4067, Australia.
Hiroaki SugaDepartment of Chemistry, Graduate School of Science, University of Tokyo, Tokyo 113-0033, Japan.ORCID 0000-0002-5298-9186
Laura S ItzhakiDepartment of Pharmacology, University of Cambridge, Cambridge CB2 1PD, United Kingdom.
Katerina Artavanis-TsakonasDepartment of Pathology, University of Cambridge, Cambridge CB2 1QP, United Kingdom.ORCID 0000-0003-1164-1965

Funding

Japan Society for the Promotion of Science (JSPS) Grant-in-Aid for Specially Promoted Research JP20H05618UKRI | Biotechnology and Biological Sciences Research Council (BBSRC) BB/R001642/1UKRI | Medical Research Council (MRC) MRC DTP studentship
6 · The paper itself

Abstract

The ubiquitin-proteasome system is essential to all eukaryotes and has been shown to be critical to parasite survival as well, including

Indexed as

PeptidesPlasmodium falciparumProtozoan ProteinsUbiquitin ThiolesteraseAntimalarialsHumansMalaria, FalciparumUbiquitinAntimalarialsPeptidesProtozoan ProteinsUbiquitinUbiquitin ThiolesteraseUCHL3 protein, humanDUBpeptidePlasmodiumubiquitinUCHL3

Identifiers

PMID38739798
PMCPMC11126973

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.