Evidence map›Paper›PMID 38739791›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2024

Clocking out and letting go to unleash green biotech applications in a photosynthetic host.

Yao Xu, Maria Luísa Jabbur, Tetsuya Mori, Jamey D Young, Carl Hirschie Johnson

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Revitalizing the "biology" in "chronobiology".Npj biological timing and sleep · 2026
    Review
  3. Review
  4. Mutations in the circadian cycle drive adaptive plasticity in cyanobacteria.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yao Xu *Department of Biological Sciences, Vanderbilt University, Nashville, TN 37235.
Maria Luísa Jabbur *Department of Biological Sciences, Vanderbilt University, Nashville, TN 37235.ORCID 0009-0007-0486-3881
Tetsuya MoriDepartment of Biological Sciences, Vanderbilt University, Nashville, TN 37235.ORCID 0000-0001-6036-5261
Jamey D YoungDepartment of Chemical and Biomolecular Engineering, Vanderbilt University, Nashville, TN 37235.ORCID 0000-0002-0871-1494
Carl Hirschie JohnsonDepartment of Biological Sciences, Vanderbilt University, Nashville, TN 37235.ORCID 0000-0003-2878-3193

Funding

Circadian Programs in BacteriaR37GM067152 · NIGMS · VANDERBILT UNIVERSITY · PI JOHNSON, CARL HIRSCHIE · 2015 to 2024
$4.1M
Regulation and Significance of Sustained Circadian OscillationsR01GM107434 · NIGMS · VANDERBILT UNIVERSITY · PI JOHNSON, CARL HIRSCHIE · 2013 to 2024
$4.0M
Circadian Programs in BacteriaR01GM067152 · NIGMS · VANDERBILT UNIVERSITY · PI JOHNSON, CARL HIRSCHIE · 2003 to 2014
$3.9M
HHS | NIH | Office of Extramural Research (OER) GM 067152HHS | NIH | Office of Extramural Research (OER) GM 107434NIGMS NIH HHS R01 GM067152NIGMS NIH HHS R01 GM107434NIGMS NIH HHS R37 GM067152U.S. Department of Energy (DOE) DE-SC0022207
6 · The paper itself

Abstract

Cyanobacteria are photosynthetic bacteria whose gene expression patterns are globally regulated by their circadian (daily) clocks. Due to their ability to use sunlight as their energy source, they are also attractive hosts for "green" production of pharmaceuticals, renewable fuels, and chemicals. However, despite the application of traditional genetic tools such as the identification of strong promoters to enhance the expression of heterologous genes, cyanobacteria have lagged behind other microorganisms such as

Indexed as

Gene Expression Regulation, BacterialPhotosynthesisBacterial ProteinsBiotechnologyCircadian ClocksCyanobacteriaPromoter Regions, GeneticBacterial Proteinsbiotechnologycircadian rhythmscyanobacteriagene expressionKaiC

Identifiers

PMID38739791
PMCPMC11127020

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.