Evidence map›Paper›PMID 38739643›Full record

ArticlePloS one2024

Imaging performance of portable and conventional ultrasound imaging technologies for ophthalmic applications.

Jack O Thomas, Josiah K To, Anderson N Vu, David Horton, Ermin Dzihic, Andrew W Browne

Abstract read
In one paragraph

Article in PloS one, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. A Novel Slit Lamp-Based System for 3D Ultrasound of the Eye.Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine · 2026
    Article
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jack O ThomasGavin Herbert Eye Institute, Department of Ophthalmology, University of California Irvine, Irvine, California, United States of America.ORCID 0009-0009-5135-5550
Josiah K ToGavin Herbert Eye Institute, Department of Ophthalmology, University of California Irvine, Irvine, California, United States of America.
Anderson N VuGavin Herbert Eye Institute, Department of Ophthalmology, University of California Irvine, Irvine, California, United States of America.ORCID 0000-0003-0820-0536
David HortonSchool of Medicine, University of California Irvine, Irvine, California, United States of America.
Ermin DzihicSchool of Medicine, University of California Irvine, Irvine, California, United States of America.
Andrew W BrowneGavin Herbert Eye Institute, Department of Ophthalmology, University of California Irvine, Irvine, California, United States of America.

Funding

In vivo 2-photon imaging of retinal biochemistry before and after retinal organoid transplantationK08EY034912 · NEI · UNIVERSITY OF CALIFORNIA-IRVINE · PI BROWNE, ANDREW W · 2023 to 2025
$583k
NEI NIH HHS K08 EY034912
6 · The paper itself

Abstract

purposeThe aim of this study was to evaluate the imaging capabilities of Butterfly iQ with conventional ophthalmic (piezoelectric) ultrasound (COU) for ophthalmic imaging.

methodsCustom phantom molds were designed and imaged with Butterfly iQ and COU to compare spatial resolution capabilities. To evaluate the clinical imaging performance of Butterfly iQ and COU, a survey containing pathological conditions from human subjects, imaged with both Butterfly iQ and COU probes, was given to three retina specialists and graded on image detail, resolution, quality, and diagnostic confidence on a ten-point Likert scale. Kruskal-Wallis analysis was performed for survey responses.

resultsButterfly iQ and COU had comparable capabilities for imaging small axial and lateral phantom features (down to 0.1 mm) of high and low acoustic reflectivity. One of three retina specialists demonstrated a statistically significant preference for COU related to resolution, detail, and diagnostic confidence, but the remaining graders showed no significant preference for Butterfly iQ or COU across all sample images presented.

conclusionThe emergence of portable ultrasound probes offers an affordable alternative to COU technologies with comparable qualitative imaging resolution down to 0.1 mm. These findings suggest the value to further study the use of portable ultrasound systems and their utility in routine eye care.

Indexed as

Phantoms, ImagingUltrasonographyEye DiseasesHumans

Identifiers

PMID38739643
PMCPMC11090327

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.