ArticleThe Journal of clinical endocrinology and metabolism2025
High AMH Levels Are Associated With Gestational Hypertension in Patients With PCOS who Underwent IVF/ICSI-ET.
Article in The Journal of clinical endocrinology and metabolism, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- High AMH levels are associated with late miscarriage in women with PCOS undergoing frozen-thawed embryo transfer.BMC pregnancy and childbirth · 2026Article
- Article
- Impact of Elevated AMH Levels on Maternal and Perinatal Outcomes in IVF Pregnancies with PCOS.Journal of clinical medicine · 2025Article
- Davydov-Moore vaginoplasty in Mayer-Rokitansky-Küster-Hauser syndrome: sexual and surgical outcomes.Archives of gynecology and obstetrics · 2025Article
- Article
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10 authors.
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Abstract
backgroundPatients with polycystic ovary syndrome (PCOS) have a higher risk of obstetric complications. The association between anti-Müllerian hormone (AMH) and gestational hypertension in these patients is poorly understood.
objectiveTo determine the association between serum AMH levels and gestational hypertension in patients with PCOS undergoing fresh embryo transfer.
methodsThis retrospective study included 649 patients with PCOS who had singleton live births after undergoing fresh embryo transfers. The association of AMH with gestational hypertension in these patients was estimated before and after propensity score matching.
resultsPatients with gestational hypertension had higher AMH levels than those without gestational hypertension. In single-factor logistic regression, the odds of gestational hypertension increased by 11.7% and 18.6% for every 1ng/mL increase in AMH before and after adjusting for confounding factors (odds ratio [OR], 1.117; 95% CI, 1.025-1.217; P = .012; adjusted OR, 1.186; 95% CI, 1.061-1.327; adjusted P = .003), respectively. The odds of gestational hypertension increased more than 100% (adjusted OR, 2.635; 95% CI, 1.132-6.137; adjusted P = .025) in the 75th percentile group (>9.30 ng/mL) and more than 3 times (adjusted OR, 4.75; 95% CI, 1.672-13.495; adjusted P = .003) in the 90th percentile group (>12.31 ng/mL) compared to the without gestational hypertension group. AMH level was still associated with gestational hypertension after propensity score matching. The area under the curve of AMH predicting gestational hypertension was 0.654 (95% CI, 0.532-0.776; P = .011) with an optimal cutoff value of 11.975 ng/mL.
conclusionHigh serum AMH level prepregnancy (especially at levels >9.30 ng/mL) indicates a high odds of gestational hypertension in patients with PCOS undergoing fresh embryo transfer.
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