Evidence map›Paper›PMID 38739290›Full record

Observational studyInternational urogynecology journal2024

Biomechanical Integrity Score of the Female Pelvic Floor for Stress Urinary Incontinence.

Peter Takacs, Dávid Rátonyi, Erzsébet Koroknai, Heather van Raalte, Vincent Lucente, Vladimir Egorov, Zoard Tibor Krasznai, Bence Kozma

Abstract readObservational StudyValidation Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in International urogynecology journal, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Peter TakacsDepartment of Obstetrics and Gynecology, Division of Female Pelvic Medicine and Reconstructive Surgery, Eastern Virginia Medical School, Norfolk, VA, USA.
Dávid RátonyiFaculty of Medicine, Department of Obstetrics and Gynecology, University of Debrecen, Nagyerdei Krt 98, 4032, Debrecen, Hungary.
Erzsébet KoroknaiFaculty of Medicine, Department of Obstetrics and Gynecology, University of Debrecen, Nagyerdei Krt 98, 4032, Debrecen, Hungary.
Heather van RaalteThe Institute for Female Pelvic Medicine & Reconstructive Surgery, Allentown, PA, USA.
Vincent LucentePrinceton Urogynecology, Princeton, NJ, USA.
Vladimir EgorovAdvanced Tactile Imaging, Ewing, NJ, USA.
Zoard Tibor KrasznaiFaculty of Medicine, Department of Obstetrics and Gynecology, University of Debrecen, Nagyerdei Krt 98, 4032, Debrecen, Hungary.
Bence KozmaFaculty of Medicine, Department of Obstetrics and Gynecology, University of Debrecen, Nagyerdei Krt 98, 4032, Debrecen, Hungary. bence.kozma@med.unideb.hu.ORCID 0000-0001-7341-5942

Funding

Tactile and ultrasound imaging fusion for functional assessment of the female pelvic floorR44HD097805 · NICHD · ADVANCED TACTILE IMAGING, INC. · PI EGOROV, VLADIMIR · 2021 to 2022
$1.7M
Stress strain imaging for detection and characterization of endometriosis, adenomyosis and uterine fibroidsR43HD109075 · NICHD · ADVANCED TACTILE IMAGING, INC. · PI EGOROV, VLADIMIR · 2023 to 2023
$300k
NICHD NIH HHS R43 HD109075NICHD NIH HHS R44 HD097805NIH HHS R43HD109075NIH HHS R44HD097805U.S. Department of Defense W81XWH1920018
6 · The paper itself

Abstract

introduction and hypothesisThis study is aimed at developing and validating a new integral parameter, the Biomechanical Integrity score (BI-score) of the female pelvic floor for stress urinary incontinence conditions.

methodsA total of 130 subjects were included in the observational cohort study; 70 subjects had normal pelvic floor conditions, and 60 subjects had stress urinary incontinence (SUI). A Vaginal Tactile Imager (VTI) was used to acquire and automatically calculate 52 biomechanical parameters for eight VTI test procedures (probe insertion, elevation, rotation, Valsalva maneuver, voluntary muscle contractions in two planes, relaxation, and reflex contraction). Statistical methods were applied (t test, correlation) to identify the VTI parameters sensitive to the pelvic SUI conditions.

resultsTwenty-seven parameters were identified as statistically sensitive to SUI development. They were subdivided into five groups to characterize tissue elasticity (group 1), pelvic support (group 2), pelvic muscle contraction (group 3), involuntary muscle relaxation (group 4), and pelvic muscle mobility (group 5). Every parameter was transformed to its standard deviation units using the dataset for normal pelvic conditions, similar to the T-score for bone density. Linear combinations with specified weights led to the composition of five component parameters for groups 1-5 and to the BI-score in standard deviation units. The p value for the BI-score has p = 4.0 × 10

conclusionsQuantitative transformations of the pelvic tissues, support structures, and functions under diseased conditions may be studied with the SUI BI-score in future research and clinical applications.

Indexed as

Muscle ContractionPelvic FloorUrinary Incontinence, StressAdultAgedBiomechanical PhenomenaCohort StudiesElasticityFemaleHumansMiddle AgedBiomechanical Integrity scoreMuscle mobilityPelvic muscle strengthPelvic supportStress urinary incontinenceTissue elasticity

Identifiers

PMID38739290
PMCPMC11245433

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.