Evidence map›Paper›PMID 38738413›Full record

ArticleAnnals of medicine2024

Health-related quality of life in patients with generalized pustular psoriasis - a Swedish register study.

Jenny M Norlin, Sofia Löfvendahl, Marcus Schmitt-Egenolf

Abstract read
In one paragraph

Article in Annals of medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Jenny M NorlinThe Swedish Institute for Health Economics (IHE), Lund, Sweden.ORCID 0000-0001-5402-1884
Sofia LöfvendahlThe Swedish Institute for Health Economics (IHE), Lund, Sweden.ORCID 0000-0001-7988-757X
Marcus Schmitt-EgenolfDepartment of Public Health and Clinical Medicine, Dermatology, Umeå University, Umeå, Sweden.ORCID 0000-0002-3858-8474

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundReal-world data on health-related quality of life (HRQoL) in generalized pustular psoriasis (GPP) are scarce and studies have been restricted in terms of instruments used for assessments.

objectiveTo assess generic and dermatology-specific HRQoL of patients with GPP compared with patients with plaque psoriasis using real-world data from the Swedish National Register for Systemic Treatment of Psoriasis.

methodsCross-sectional data from 2006 to 2021 including 7041 individuals with plaque psoriasis without GPP and 80 patients with GPP, of which 19% also had plaque psoriasis. Total scores for the EuroQol-5 Dimensions (EQ-5D) and Dermatology Life Quality Index (DLQI), as well as degree of severity within the instruments' dimensions/questions, were compared between patient groups.

resultsEQ-5D scores were significantly (

conclusionsIndividuals with GPP have a considerable impairment in both generic and dermatology-specific HRQoL. The HRQoL was significantly worse in individuals with GPP compared to individuals with plaque psoriasis. The significant HRQoL impairment of GPP shows the potential value of better healthcare interventions for this multisystem disease.

Indexed as

PsoriasisQuality of LifeRegistriesSeverity of Illness IndexAdultAgedCross-Sectional StudiesFemaleHumansMaleMiddle AgedSurveys and QuestionnairesSwedenDermatology Life Quality IndexEuroQol-5 dimensionsGeneralized pustular psoriasishealth-related quality of lifereal-world data

Identifiers

PMID38738413
PMCPMC11095275

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.