Evidence map›Paper›PMID 38738169›Full record

ArticleChem2024

Influence of structural moieties in squaraine dyes on optoacoustic signal shape and intensity.

William M MacCuaig, Carly Wickizer, Richard S Van, Emmanuel R Buabeng, Megan R Lerner, William E Grizzle, Yihan Shao, Maged Henary, Lacey R McNally

Erratum issuedAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Chem, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Assessment of Breast Tumors Using Multispectral Optoacoustic Tomography in a Surgical Setting.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2025
    Trial
  2. Article
  3. Review
  4. Article
  5. Theranostic nanoparticles for detection and treatment of pancreatic cancer.Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

William M MacCuaigStephenson Cancer Center, University of Oklahoma, Oklahoma City, OK 73104, USA.
Carly WickizerDepartment of Chemistry and Biochemistry, University of Oklahoma, Norman, OK 73019, USA.
Richard S VanDepartment of Chemistry and Biochemistry, University of Oklahoma, Norman, OK 73019, USA.
Emmanuel R BuabengDepartment of Chemistry, Georgia State University, Atlanta, GA 30303, USA.
Megan R LernerDepartment of Surgery, University of Oklahoma, Oklahoma City, OK 73104, USA.
William E GrizzleDepartment of Pathology, University of Alabama at Birmingham, Birmingham, AL 35294, USA.
Yihan ShaoDepartment of Chemistry and Biochemistry, University of Oklahoma, Norman, OK 73019, USA.
Maged HenaryDepartment of Chemistry, Georgia State University, Atlanta, GA 30303, USA.
Lacey R McNallyStephenson Cancer Center, University of Oklahoma, Oklahoma City, OK 73104, USA.

Funding

Tissue Pathology Shared ResourceP30CA225520 · NCI · UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR · PI ROBERT S. MANNEL · 2018 to 2026
$27.1M
Development of contrast agents to facilitate image-guided surgeryR01CA281098 · NCI · UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR · PI JAIN, AJAY, MCNALLY, LACEY R · 2023 to 2025
$2.9M
Non-Invasive Detection of Tumor Extracellular pH using Multispectral Optoacoustic TomographyR01CA205941 · NCI · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI MCNALLY, LACEY R · 2016 to 2021
$1.7M
Development of an apoptosis biosensor for monitoring of breast cancerR01EB034731 · NIBIB · UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR · PI HENARY, MAGED M, MCNALLY, LACEY R · 2023 to 2025
$1.5M
Multiscale Modeling of Enzymatic Reactions and Firefly BioluminescenceR01GM135392 · NIGMS · UNIVERSITY OF OKLAHOMA · PI SHAO, YIHAN · 2019 to 2022
$1.0M
Tumor-Specific Nanocontrast Agents for Improved Detection of Pancreatic CancerF31CA261044 · NCI · UNIVERSITY OF OKLAHOMA · PI MACCUAIG, WILLIAM · 2022 to 2023
$79k
NCI NIH HHS F31 CA261044NCI NIH HHS P30 CA225520NCI NIH HHS R01 CA205941NCI NIH HHS R01 CA281098NIBIB NIH HHS R01 EB034731NIGMS NIH HHS R01 GM135392
6 · The paper itself

Abstract

Optoacoustic imaging has grown in clinical relevance due to inherent advantages in sensitivity, resolution, and imaging depth, but the development of contrast agents is lacking. This study assesses the influence of structural features of squaraine dyes on optoacoustic activity through computational models,

Identifiers

PMID38738169
PMCPMC11087056

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.