Evidence map›Paper›PMID 38737989›Full record

ArticleAdvanced intelligent systems (Weinheim an der Bergstrasse, Germany)2023

Coupling magnetic torque and force for colloidal microbot assembly and manipulation.

Coy J Zimmermann, Andrew J Petruska, Keith B Neeves, David W M Marr

Abstract read
In one paragraph

Article in Advanced intelligent systems (Weinheim an der Bergstrasse, Germany), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Magnetically powered microwheel thrombolysis of occlusive thrombi in zebrafish.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Coy J ZimmermannDepartment of Chemical and Biological Engineering, Colorado School of Mines, Golden, CO, USA.
Andrew J PetruskaDepartment of Mechanical Engineering, Colorado School of Mines, Golden, CO, USA.
Keith B NeevesDepartments of Bioengineering and Pediatrics, University of Colorado Denver | Anschutz Medical Campus, Aurora, CO.
David W M MarrDepartment of Chemical and Biological Engineering, Colorado School of Mines, Golden, CO, USA.

Funding

Magnetically propelled microwheels for rapid thrombolysis in small arteriesR01NS102465 · NINDS · COLORADO SCHOOL OF MINES · PI MARR, DAVID WM, NEEVES, KEITH B · 2018 to 2022
$2.6M
Airborne delivery of microbots for chemical and mechanical attack of pulmonary biofilmsR21AI138214 · NIAID · COLORADO SCHOOL OF MINES · PI MARR, DAVID WM, NEEVES, KEITH B · 2019 to 2020
$419k
NIAID NIH HHS R21 AI138214NINDS NIH HHS R01 NS102465
6 · The paper itself

Abstract

For targeted transport in the body, biomedical microbots (μbots) must move effectively in three-dimensional (3D) microenvironments. Swimming μbots translate via asymmetric or screw-like motions while rolling ones use friction with available surfaces to generate propulsive forces. We have previously shown that planar rotating magnetic fields assemble μm-scale superparamagnetic beads into circular μbots that roll along surfaces. In this, gravity is required to pull μbots near the surface; however, this is not necessarily practical in complex geometries. Here we show that rotating magnetic fields, in tandem with directional magnetic gradient forces, can be used to roll μbots on surfaces regardless of orientation. Simplifying implementation, we use a spinning permanent magnet to generate differing ratios of rotating and gradient fields, optimizing control for different environments. This use of a single magnetic actuator sidesteps the need for complex electromagnet or tandem field setups, removes requisite gravitational load forces, and enables μbot targeting in complex 3D biomimetic microenvironments.

Identifiers

PMID38737989
PMCPMC11086969

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.