Evidence map›Paper›PMID 38737493›Full record

ArticleJournal of medical imaging (Bellingham, Wash.)2024

Computerized assessment of background parenchymal enhancement on breast dynamic contrast-enhanced-MRI including electronic lesion removal.

Lindsay Douglas, Jordan Fuhrman, Qiyuan Hu, Alexandra Edwards, Deepa Sheth, Hiroyuki Abe, Maryellen Giger

Abstract read
In one paragraph

Article in Journal of medical imaging (Bellingham, Wash.), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Lindsay DouglasUniversity of Chicago, Department of Radiology Committee on Medical Physics, Chicago, Illinois, United States.ORCID https://orcid.org/0000-0002-4695-6441
Jordan FuhrmanUniversity of Chicago, Department of Radiology Committee on Medical Physics, Chicago, Illinois, United States.
Qiyuan HuUniversity of Chicago, Department of Radiology Committee on Medical Physics, Chicago, Illinois, United States.ORCID https://orcid.org/0000-0002-3326-6441
Alexandra EdwardsUniversity of Chicago, Department of Radiology Committee on Medical Physics, Chicago, Illinois, United States.
Deepa ShethUniversity of Chicago, Department of Radiology Committee on Medical Physics, Chicago, Illinois, United States.
Hiroyuki AbeUniversity of Chicago, Department of Radiology Committee on Medical Physics, Chicago, Illinois, United States.
Maryellen GigerUniversity of Chicago, Department of Radiology Committee on Medical Physics, Chicago, Illinois, United States.ORCID https://orcid.org/0000-0001-5482-9728

Funding

MEDICAL IMAGING AND DATA RESOURCE CENTER (MIDRC) YEAR 375N92020D00021 · NIBIB · UNIVERSITY OF CHICAGO · PI GIGER, MARYELLEN · 2021 to 2025
$16.6M
RESEARCH TRAINING IN MEDICAL PHYSICST32EB002103 · NIBIB · UNIVERSITY OF CHICAGO · PI ARMATO, SAMUEL G. · 2003 to 2019
$4.7M
Protected Radiomics Analysis Commons for Deep Learning in Biomedical DiscoveryS10OD025081 · OD · UNIVERSITY OF CHICAGO · PI GIGER, MARYELLEN L. · 2018 to 2018
$339k
High-Performance Computer Cluster for Image AnalysisS10RR021039 · NCRR · UNIVERSITY OF CHICAGO · PI NISHIKAWA, ROBERT M · 2007 to 2007
$230k
NCRR NIH HHS S10 RR021039NHLBI NIH HHS 75N92020D00021NIBIB NIH HHS T32 EB002103NIH HHS S10 OD025081
6 · The paper itself

Abstract

Purpose: Current clinical assessment qualitatively describes background parenchymal enhancement (BPE) as minimal, mild, moderate, or marked based on the visually perceived volume and intensity of enhancement in normal fibroglandular breast tissue in dynamic contrast-enhanced (DCE)-MRI. Tumor enhancement may be included within the visual assessment of BPE, thus inflating BPE estimation due to angiogenesis within the tumor. Using a dataset of 426 MRIs, we developed an automated method to segment breasts, electronically remove lesions, and calculate scores to estimate BPE levels. Approach: A U-Net was trained for breast segmentation from DCE-MRI maximum intensity projection (MIP) images. Fuzzy Results: Statistically significant trends were found between radiologist BPE ratings and calculated BPE scores for all breast regions (Kendall correlation, Conclusions: Results demonstrate the potential for automatic BPE scoring to serve as a quantitative value for objective BPE level classification from breast DCE-MR without the influence of lesion enhancement.

Indexed as

background parenchymal enhancementbreast MRIfuzzy c-meansmachine learningU-Net

Identifiers

PMID38737493
PMCPMC11086664

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.