ArticlePatient preference and adherence2024
Effects of Social Support on Medication Adherence Among Patients with Schizophrenia: Serial Multiple Mediation Model.
Article in Patient preference and adherence, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed.
- Bridge Nodes Linking Depression and Medication Taking Self-Efficacy Dimensions Among Persons With HIV: A Secondary Data Analysis.AIDS and behavior · 2025Trial
- Integrated Psychological-Behavioral Predictive Model Using Explainable Machine Learning.Healthcare (Basel, Switzerland) · 2026Article
- Associations among subjective cognitive complaints, perceived social support, and medication adherence in patients with psychotic disorders.Frontiers in psychiatry · 2026Article
- Experiences of an unconditional cash transfer intervention among young adults with first-episode psychosis in South Africa: qualitative inquiry of patients and their caregivers.International journal of qualitative studies on health and well-being · 2025Article
- Mental health literacy and the stigmatisation and discrimination of individuals affected by mental illnesses in China: a scoping review.The Lancet regional health. Western Pacific · 2025Review
- Article
- Correlation Between Social Support, Patient Satisfaction, and Associated Factors in Patients with Schizophrenia.Cureus · 2025Article
- Social support and its associated factors among older adult patients with intestinal stomas: a cross-sectional study in Guangxi, China.Frontiers in public health · 2025Article
- The Psychology Behind the Efficacy of a Buddy System for Enhancing Retention in Dermatological Clinical Trials.Cureus · 2024Review
- Exploring the impact of subjective well-being on medication adherence: A cross-sectional study among individuals with multiple chronic diseases.Exploratory research in clinical and social pharmacy · 2024Article
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Abstract
Purpose: This study aims to explore the serial mediating effect of stigma and depression on the association between social support and medication adherence. Patients and Methods: A cross-sectional survey was undertaken in the Changning District of Shanghai using a five-part questionnaire from August to December 2023. A convenient sampling method was employed, and 35 patients with schizophrenia were invited from each of the 9 streets in Changning District to participate in the survey, resulting in a total of 305 valid questionnaires collected. The questionnaire measured social support, stigma, depression, medication adherence, and demographic characteristics. Data analysis involved descriptive statistics, independent samples t-tests, ANOVA, Pearson correlation analysis, and the bootstrap method. Results: There was a direct and significantly positive association between social support and medication adherence (β = 0.69, p < 0.001). Moreover, increased levels of stigma (β = - 0.45, p = 0.013) and depression (β = - 0.09, p = 0.017) were both associated with a decline in medication adherence. Bootstrapping analysis revealed that the association between social support and medication adherence operated indirectly through stigma (β = 0.11, 95% CI: 0.03, 0.18). Additionally, social support was indirectly associated with medication adherence through depression (β = 0.15, 95% CI: 0.04, 0.30). Further analysis indicated that social support had an indirect association with medication adherence through both stigma and depression (β = 0.04, 95% CI: 0.01, 0.07). Conclusion: Stigma and depression serially mediate the association between social support and medication adherence among patients with schizophrenia. This serial multiple mediation model underscores the importance of integrating social support interventions with psychological interventions aimed at reducing stigma and depression, thereby effectively enhancing medication adherence in patients with schizophrenia.
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