Evidence map›Paper›PMID 38737433›Full record

ArticleOpen forum infectious diseases2024

Pharmacist-Driven Rapid Initiation of Antiretroviral Therapy Decreases Time to Viral Suppression in People With HIV.

Amy L Brotherton, Ann-Marie Coroniti, Diane K Ayuninjam, Martha C Sanchez, Gregorio Benitez, Joseph M Garland

Abstract read
In one paragraph

Article in Open forum infectious diseases, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Amy L BrothertonDepartment of Pharmacy, The Miriam Hospital Infectious Diseases and Immunology Center, Providence, Rhode Island, USA.ORCID https://orcid.org/0000-0003-3975-6932
Ann-Marie CoronitiDepartment of Pharmacy, Healthcare Associates, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA.
Diane K AyuninjamDepartment of Pharmacy, The Miriam Hospital Infectious Diseases and Immunology Center, Providence, Rhode Island, USA.
Martha C SanchezDivision of Infectious Diseases, Department of Medicine, The Miriam Hospital Infectious Diseases and Immunology Center, Providence, Rhode Island, USA.
Gregorio BenitezDivision of Infectious Diseases, Department of Medicine, The Miriam Hospital Infectious Diseases and Immunology Center, Providence, Rhode Island, USA.
Joseph M GarlandDivision of Infectious Diseases, Department of Medicine, The Miriam Hospital Infectious Diseases and Immunology Center, Providence, Rhode Island, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Rapid initiation of antiretroviral therapy (rapid ART) improves clinical outcomes in people with HIV and is endorsed by clinical guidelines. However, logistical challenges limit widespread implementation. We describe an innovative rapid ART model led by pharmacists and its impact on clinical outcomes, including time to viral suppression (TVS). Methods: On 1 January 2019, we implemented Pharmacist-Driven Rapid ART (PHARM-D RAPID ART), including rapid ART initiation by pharmacists. Our retrospective cohort study compared TVS, using a Cox proportional hazards model, and clinical outcomes among individuals with a new HIV diagnosis before (1 January 2017 to 31 December 2017) and after (1 January 2019 to 31 December 2019) implementation. Results: A total of 108 individuals were included. TVS was significantly shorter ( Conclusions: A pharmacist-driven model for rapid ART delivery decreases TVS with high rates of retention in care and durable VS. This model could improve clinical outcomes and increase program feasibility and sustainability.

Indexed as

antiretroviral therapyHIVpharmacistrapid ARTviral suppression

Identifiers

PMID38737433
PMCPMC11088354

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.