ArticleEuropean heart journal open2024
Association between lipoprotein(a) and premature atherosclerotic cardiovascular disease: a systematic review and meta-analysis.
Article in European heart journal open, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
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Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Association of Lp(a) with coronary plaque burden and high-risk plaque features: A meta-analysis of imaging studies.Atherosclerosis · 2026Pooled it
- Association of lipoprotein(a) with the angiographic extent of coronary artery disease and selected angiographic findings in patients with acute coronary syndromes.Atherosclerosis plus · 2026Article
- Expert consensus on Lipoprotein(a) in the Gulf countries: Navigating cardiovascular risk and therapeutic advances.Atherosclerosis plus · 2026Article
- Association of lipoprotein(a) and composite inflammatory indices with functional outcomes in acute ischemic stroke: a prospective cohort study.Lipids in health and disease · 2026Article
- Impact of Lipoprotein(a) on Residual Cardiovascular Risk After an Acute Coronary Syndrome.Journal of clinical medicine · 2026Review
- Distribution of Lipoprotein(a) Levels and Clinical Associations in a Lebanese Adult Population: A Retrospective Observational Study.Journal of clinical medicine · 2026Article
- Prognostic value of lipoprotein(a) in a primary prevention ambulatory cohort.Clinical research in cardiology : official journal of the German Cardiac Society · 2026Article
- Joint effects of severe obesity and inflammation on mortality in critically ill non-ST-segment elevation myocardial infarction patients: a cohort study with external validation.Frontiers in endocrinology · 2026Article
- Novel lipid parameters for predicting and interpreting the severity of coronary artery lesions in premature coronary artery disease.Frontiers in cardiovascular medicine · 2026Article
- Unraveling Emerging Data on Lipoprotein(a)-Driven Cardiovascular Disease via Multiomics: A Review.Global heart · 2026Review
- Lipoprotein(a), family history, and incidence of premature ASCVD events in a pooled US cohort.American journal of preventive cardiology · 2025Article
- Ethnic Variation in Lipoprotein(a) Levels in the Kazakhstan Population.Journal of clinical medicine · 2025Article
- Lipoprotein(a) Levels and the Risk of Coronary Heart Disease and Stroke: The Suita Study.Journal of atherosclerosis and thrombosis · 2025Article
- Lipoprotein(a) and Cardiovascular Risk in Asian Populations: A Comprehensive Review.Journal of lipid and atherosclerosis · 2025Review
- Statins-Their Effect on Lipoprotein(a) Levels.Reviews in cardiovascular medicine · 2025Review
- Construction of diagnostic and prognostic models for premature coronary artery disease based on multiple machine algorithms.Frontiers in cardiovascular medicine · 2025Article
- Intervention, improved prevention, imaging, inflammation, and innovation: the five I's cardiovascular highlights inEuropean heart journal open · 2025Article
- TyG index and CBC-derived inflammatory indicators individual and mixed effects on all-cause and cardiovascular disease deaths in patients with CHD.Frontiers in cardiovascular medicine · 2025Article
- New data allow to better understand the secrets of lipoprotein(a): is that for sure?European heart journal open · 2024Article
- The relationship between system inflammation response index and coronary heart disease: a cross-sectional study (NHANES 2007-2016).Frontiers in cardiovascular medicine · 2024Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Aims: High lipoprotein(a) [Lp(a)] level has been demonstrated as an important risk factor for atherosclerotic cardiovascular diseases (ASCVD) amongst the older populations, whereas its effects in the younger population remain unclear. This study evaluated the associations between Lp(a) and the risk of premature ASCVD. Method and results: PubMed and Embase were searched for related studies until 12 November 2023. Fifty-one studies including 100 540 participants were included. Mean age of patients ranged from 35.3 to 62.3 years. The proportion of male participants ranged from 0% to 100%. The mean follow-up was provided in five studies ranging from 1 year to 40 years. The definition of elevated Lp(a) varied among studies, such as >30 mg/dL, >50 mg/dL, the top tertiles, the top quartiles, the top quintiles, and so on. Higher Lp(a) was significantly associated with the composite ASCVD [odds ratio (OR): 2.15, 95% confidence interval (95% CI): 1.53-3.02, Conclusion: Elevated Lp(a) predicts the risk of the composite or individual ASCVD in young, regardless of study design, gender, population characteristics (community or hospitalized), different premature definitions, and various Lp(a) measurement approaches. This association was important in South Asians, Caucasians, FH patients, T2DM patients, and patients with baseline LDL-c level ≥ 2.6 mmol/L.
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