Evidence map›Paper›PMID 38737334›Full record

ReviewFrontiers in molecular biosciences2024

A systematic review reveals conflicting evidence for the prevalence of antibodies against the sialic acid 'xenoautoantigen' Neu5Gc in humans and the need for a standardised approach to quantification.

Esme Hutton, Emma Scott, Craig N Robson, Nathalie Signoret, Martin A Fascione

Abstract readReview
In one paragraph

Review in Frontiers in molecular biosciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Esme HuttonDepartment of Chemistry, University of York, York, United Kingdom.
Emma ScottNewcastle University, Centre for Cancer, Newcastle University Biosciences Institute, Newcastle, United Kingdom.
Craig N RobsonNewcastle University, Centre for Cancer, Newcastle University Translational and Clinical Research Institute, Newcastle, United Kingdom.
Nathalie SignoretHull York Medical School, University of York, York, United Kingdom.
Martin A FascioneDepartment of Chemistry, University of York, York, United Kingdom.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Despite an array of hypothesised implications for health, disease, and therapeutic development, antibodies against the non-human sialic acid

Indexed as

anti-Neu5Gc antibodiesglycoscienceNeu5Gcsialic acidxeno-autoantigen

Identifiers

PMID38737334
PMCPMC11082328

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.