Evidence map›Paper›PMID 38736958›Full record

ArticleMediterranean journal of rheumatology2024

Safety of COVID-19 Vaccine in Patients with Rheumatic and Musculoskeletal Diseases.

Ali Abdulrahman Younis, Asal Adnan Ridha, Yasameen Abbas Humadi, Nizar Abdulateef Jassim, Nabaa Ihsan Awadh, Avin Maroof, Ali Mohammed Hussein Alqazzaz, Faiq I Gorial, Taha Ahmed Qaradaghi, Zahraa Salam Abdulzahra and 6 more

Abstract read
In one paragraph

Article in Mediterranean journal of rheumatology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Ali Abdulrahman YounisDepartment of Medicine, College of Medicine, University of Mosul, Mosul, Iraq.
Asal Adnan RidhaRheumatology Unit, Department of Internal Medicine, Baghdad Teaching Hospital, Medical City, Iraq.
Yasameen Abbas HumadiAl-Nahrain University, College of Medicine, Baghdad, Iraq.
Nizar Abdulateef JassimRheumatology Unit, Department of Medicine, College of Medicine, University of Baghdad, Iraq.
Nabaa Ihsan AwadhRheumatology Unit, Department of Internal Medicine, Baghdad Teaching Hospital, Medical City, Iraq.
Avin MaroofSchool of Medicine, University of Kurdistan-Hawler, Erbil, Kurdistan Region, Iraq.
Ali Mohammed Hussein AlqazzazDepartment of Medicine, College of Medicine, University of Babylon, Iraq.
Faiq I GorialRheumatology Unit, Department of Internal Medicine, Baghdad Teaching Hospital, Medical City, Iraq.
Taha Ahmed QaradaghiSulaymaniyah Internal Medicine Teaching Hospital, Sulaymaniyah, Iraq.
Zahraa Salam AbdulzahraRheumatology Unit, Department of Internal Medicine, Baghdad Teaching Hospital, Medical City, Iraq.
Zainab A MahmoodCollege of Medicine, University of Basrah, Basrah, Iraq.
Noor Talal YaseenRheumatology Unit, Department of Internal Medicine, Baghdad Teaching Hospital, Medical City, Iraq.
Duaa Nidhal AlIdrecyAl-Imamain Al-Kadhimin Medical City, Baghdad, Iraq.
Israa Talib HakmanBaghdad Teaching Hospital, Baghdad, Iraq.
Saja Jabbar TarfahBaghdad Teaching Hospital, Baghdad, Iraq.
Adil Saudi KhudhairBaghdad Teaching Hospital, Baghdad, Iraq.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: The main purpose of this study was to determine the frequency of COVID-19 vaccine side effects in patients with rheumatic diseases and to examine any potential associations with medications, disease type, or comorbidities. Methods: A multicentre cross-sectional study from rheumatology units in different hospitals in Iraq was carried out between 8 Results: A total of 661 (57.8% female, mean age 46.51± 12.97 years) patients with rheumatic illnesses who received the "COVID-19" vaccination were included in this study. Rheumatoid arthritis was the most frequent diagnostic group. The Pfizer vaccine was given to the majority of patients (74.6%), followed by Sinopharm (16.2%), and AstraZeneca (9.2%). Side effects were detected in 661(100%) and 528 (100%) patients following the first and second vaccination doses, respectively; among which the most frequent were injection site pain in 57.8% following the first dose and 47.6% after the second dose, followed by fatigue and fever. According to multivariate logistic regression models, age (B=-0.204, p = 0.000), had a significantly inverse correlation coefficient with the experience of greater side effects. Rheumatic disease flares reported in 9.9%, 10.3%, and 8.2% of patients who received the Pfizer, Sinopharm, and AstraZeneca vaccines, respectively. Conclusion: The "COVID-19" vaccination has a reassuring safety profile with no greater risk of adverse events in any specific illness or pharmacological therapy.

Indexed as

COVID-19flarerheumatic diseasessafetyvaccine

Identifiers

PMID38736958
PMCPMC11082777

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.