Evidence map›Paper›PMID 38736937›Full record

ArticleMaedica2024

Molecular Mechanisms of Biofilm Formation on Orthopaedic Implants: Review of the Literature.

Matthaios Bakalakos, Margarita-Michaela Ampadiotaki, Christos Vlachos, Nikolaos Sipsas, Spiros Pneumaticos, John Vlamis

Abstract readEditorial
In one paragraph

Article in Maedica, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Matthaios Bakalakos3rd Orthopaedic Department, National and Kapodistrian University of Athens, KAT General Hospital, Athens, Greece.
Margarita-Michaela Ampadiotaki2nd Orthopaedic Department, KAT General Hospital, Athens, Greece.
Christos Vlachos3rd Orthopaedic Department, National and Kapodistrian University of Athens, KAT General Hospital, Athens, Greece.
Nikolaos SipsasInfectious Diseases, National and Kapodistrian University of Athens, Athens, Greece.
Spiros Pneumaticos3rd Orthopaedic Department, National and Kapodistrian University of Athens, KAT General Hospital, Athens, Greece.
John Vlamis3rd Orthopaedic Department, National and Kapodistrian University of Athens, KAT General Hospital, Athens, Greece.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Orthopaedic implant-associated infections (OIAIs) is one of the most catastrophic complications following joint arthroplasty or fracture fixation. Given the increasing number of orthopaedic implants which are used annually, periprosthetic infections emerge as a global problem. Their diagnosis and consequent therapeutic management remain challenging for clinicians. Biofilm formation is a complex and only partially understood process that has not been extensively studied. Understanding the underlying mechanisms involved in biofilm formation is crucial in the amelioration of both diagnosis and therapeutic management of OIAIs. We performed a literature review of the molecular mechanisms of biofilm formation and discussed the four most common and thoroughly researched microbes of biofilm-related OIAIs.

Identifiers

PMID38736937
PMCPMC11079743

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.