Evidence map›Paper›PMID 38736584›Full record

ArticleBMJ neurology open2024

Educational attainment, severity and short-term prognosis of intracerebral haemorrhage.

Nirupama Yechoor, Pamela Rist, Alena Ganbold, Christina Kourkoulis, Samantha Mora, Ernst Mayerhofer, Livia Parodi, Lindsay Rosenfeld, Christopher D Anderson, Jonathan Rosand

Abstract read
In one paragraph

Article in BMJ neurology open, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Nirupama YechoorMassachusetts General Hospital, Boston, Massachusetts, USA.ORCID 0000-0001-6479-9155
Pamela RistDepartment of Medicine, Harvard Medical School, Boston, Massachusetts, USA.
Alena GanboldMassachusetts General Hospital, Boston, Massachusetts, USA.
Christina KourkoulisMassachusetts General Hospital, Boston, Massachusetts, USA.
Samantha MoraMassachusetts General Hospital, Boston, Massachusetts, USA.
Ernst MayerhoferMassachusetts General Hospital, Boston, Massachusetts, USA.
Livia ParodiMassachusetts General Hospital, Boston, Massachusetts, USA.
Lindsay RosenfeldBrandeis University, Waltham, Massachusetts, USA.
Christopher D AndersonMassachusetts General Hospital, Boston, Massachusetts, USA.
Jonathan RosandMassachusetts General Hospital, Boston, Massachusetts, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Educational attainment is a critical social determinant of health that impacts the risk and severity of incident ischaemic stroke, but less is known of its impact on intracerebral haemorrhage (ICH). The objective of this study is to determine whether educational attainment is associated with ICH severity and short-term prognosis. Methods: Subjects were enrolled in a prospectively ascertained cohort with primary ICH from 1994 to 2020 at Massachusetts General Hospital. Educational attainment, medical history of ICH risk factors, ICH volume and ICH score were obtained on admission. The primary outcomes were ICH volume and the ICH score. Results: Of 2539 eligible patients eligible, the median age of the sample was 74 (IQR 64-82) and 2159 (85%) had high school-only education. 1655 (65%) presented with an ICH volume less than or equal to 30 mL and 1744 (69%) presented with an ICH score less than 3. In multivariable logistic regression analyses controlling for age, income, employment history and prestroke diagnoses of hypertension and coronary artery disease, patients with high school-only education were more likely to have an ICH volume greater than 30 mL compared with college diplomates (OR 1.58, 95% CI 1.24 to 2.08) and more likely to have an ICH score of 3 or greater compared with college diplomates (OR 2.37, 95% CI 1.77 to 3.19). Discussion: Prestroke educational attainment is independently associated with ICH severity and short-term prognosis, with lower educational attainment associated with larger ICH volumes and higher ICH scores. Future studies should examine how educational attainment impacts exposure to traditional clinical risk factors.

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INTENSIVE CARESTROKE

Identifiers

PMID38736584
PMCPMC11085696

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